Paluszkiewicz Patrycja, Martuszewski Adrian, Radziejewska Jadwiga, Zawadzki Jacek, Smereka Jacek, Gajek Jacek
Department of Emergency Medical Service, Wroclaw Medical University, ul. Parkowa 34, 51-616 Wrocław, Poland.
Division of Environmental Health and Occupational Medicine, Department of Population Health, Wroclaw Medical University, Mikulicza-Radeckiego 7, 50-368 Wrocław, Poland.
Biomedicines. 2024 Oct 16;12(10):2356. doi: 10.3390/biomedicines12102356.
His bundle pacing (HBP) and left bundle branch pacing (LBBP) are emerging therapies for patients with heart failure and conduction disorders, offering potential advantages over traditional pacing methods. These approaches aim to restore physiological conduction and improve cardiac function more effectively.
This study aims to evaluate the efficacy and safety of HBP and LBBP in patients with heart failure and conduction disturbances, comparing these techniques to conventional pacing.
A comprehensive review of recent studies and clinical trials was conducted, focusing on the performance of HBP and LBBP in improving cardiac function, reducing QRS duration, and enhancing overall patient outcomes. The analysis includes data on clinical efficacy, procedural safety, and long-term benefits associated with these pacing modalities.
Both HBP and LBBP have demonstrated significant improvements in cardiac function and clinical outcomes compared to conventional pacing. HBP effectively restores physiological conduction with improved synchronization and a reduction in QRS duration. LBBP has shown enhanced left ventricular activation, leading to better overall cardiac performance. Both techniques have been associated with a lower incidence of complications and a higher success rate in achieving optimal pacing thresholds.
HBP and LBBP offer promising alternatives to traditional pacing for patients with heart failure and conduction disorders. These advanced pacing strategies provide superior clinical outcomes and improved cardiac function with reduced risk of complications. Further research and clinical trials are needed to fully establish the long-term benefits and safety profiles of these techniques in diverse patient populations.
希氏束起搏（HBP）和左束支起搏（LBBP）是针对心力衰竭和传导障碍患者的新兴治疗方法，与传统起搏方法相比具有潜在优势。这些方法旨在更有效地恢复生理性传导并改善心脏功能。
本研究旨在评估HBP和LBBP在心力衰竭和传导障碍患者中的疗效和安全性，并将这些技术与传统起搏进行比较。
对近期的研究和临床试验进行了全面综述，重点关注HBP和LBBP在改善心脏功能、缩短QRS波时限以及提高患者总体预后方面的表现。分析包括与这些起搏方式相关的临床疗效、操作安全性和长期益处的数据。
与传统起搏相比，HBP和LBBP均已证明在心脏功能和临床结局方面有显著改善。HBP有效地恢复了生理性传导，同步性得到改善，QRS波时限缩短。LBBP显示出左心室激活增强，导致整体心脏性能更好。这两种技术的并发症发生率均较低，且达到最佳起搏阈值的成功率较高。
对于心力衰竭和传导障碍患者，HBP和LBBP为传统起搏提供了有前景的替代方案。这些先进的起搏策略提供了卓越的临床结局，改善了心脏功能，同时降低了并发症风险。需要进一步的研究和临床试验来全面确定这些技术在不同患者群体中的长期益处和安全性。
