Nicholas Andrew, Spraul Allison, Fleischer Alan B
Department of Dermatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
J Clin Med. 2024 Oct 21;13(20):6275. doi: 10.3390/jcm13206275.
: Aggregate prescribing behavior for inflammatory lesions of rosacea has been described, but individual physician behavior has not been characterized. This study aims to assess the modern state of topical rosacea drug selection by analyzing prescribing patterns among individual dermatologists. We assessed utilization patterns of four topical papulopustular rosacea agents in 2021 Medicare Part-D data. K-means cluster analysis identified prescriber phenotypes based on the proportion of claims for each drug by physician. : Cluster analysis identified four prescriber phenotypes for topical rosacea agents, with the majority favoring metronidazole. In each of the other clusters, metronidazole was co-prescribed alongside the primary agent. Significant predictors of phenotype included patient ages, patient risk scores, and a group practice setting. : The study reveals nonuniform prescribing patterns for topical papulopustular rosacea treatments among U.S. dermatologists. While aggregate data indicate diverse drug utilization, cluster analysis suggests that individual prescribers tend to use a limited selection of agents.
酒渣鼻炎性皮损的总体处方行为已有描述，但个体医生的行为特征尚未明确。本研究旨在通过分析个体皮肤科医生的处方模式，评估酒渣鼻局部用药选择的现代状况。我们在2021年医疗保险D部分数据中评估了四种酒渣鼻丘疹脓疱型局部用药的使用模式。K均值聚类分析根据医生对每种药物的索赔比例确定了处方者表型。聚类分析确定了酒渣鼻局部用药的四种处方者表型，大多数人倾向于使用甲硝唑。在其他每个聚类中，甲硝唑与主要药物联合使用。表型的显著预测因素包括患者年龄、患者风险评分和团体执业环境。该研究揭示了美国皮肤科医生在酒渣鼻丘疹脓疱型局部治疗方面的处方模式不一致。虽然总体数据表明药物使用存在差异，但聚类分析表明个体处方者倾向于使用有限的几种药物。
