Blake D J
South Med J. 1986 Feb;79(2):201-4. doi: 10.1097/00007611-198602000-00016.
The diagnostic concept of posttraumatic stress disorder (PTSD) has long been recognized but usually applied in postwar circumstances. Recently developed criteria have allowed the disorder to be recognized in civilian patients having stress from such common insults as trauma, burns, or rape. Because PTSD may become chronic and difficult to treat if unrecognized, early intervention is desirable. In this report I describe three patients with acute PTSD who had favorable therapeutic response to tricyclic antidepressants. Although the use of the tricyclic agents in PTSD is rational because of their antianxiety and antidepressant properties, little has previously been said of their effectiveness in this disorder. These agents may provide an effective means of diminishing or preventing chronic PTSD.
创伤后应激障碍（PTSD）的诊断概念早已得到认可，但通常应用于战后情况。最近制定的标准使这种障碍能够在遭受创伤、烧伤或强奸等常见伤害而产生压力的平民患者中得到识别。由于PTSD如果未被识别可能会变得慢性且难以治疗，所以早期干预是可取的。在本报告中，我描述了三名急性PTSD患者，他们对三环类抗抑郁药有良好的治疗反应。尽管由于三环类药物具有抗焦虑和抗抑郁特性，在PTSD中使用它们是合理的，但此前很少有人提及它们在这种障碍中的有效性。这些药物可能提供一种减轻或预防慢性PTSD的有效方法。
