Lepine J P, Darves-Bornoz J M
Service de Psychiatrie, CHU Bichat-Claude-Bernard, Paris, France.
Acta Psychiatr Belg. 1993 May-Jun;93(3):121-35.
This paper reviews different psychotherapeutic and drug treatments for Post Traumatic Stress Disorder (PTSD). Psychotherapeutic treatments have changed from the abreaction technique to more classical psychodynamic approaches and recently to cognitive and behavioral techniques. Many drugs have been used in the treatment of PTSD but most of the studies were not controlled and included very few patients. More recently, double blind controlled studies have been performed comparing imipramine, desipramine, amitriptyline, phenelzine and placebo. A global efficacy has been found but the improvement was more closely related to associated symptoms, namely anxiety and depression, than to the core symptoms of PTSD.
本文综述了创伤后应激障碍（PTSD）的不同心理治疗和药物治疗方法。心理治疗方法已从宣泄技术转变为更经典的心理动力学方法，最近又转变为认知和行为技术。许多药物已用于PTSD的治疗，但大多数研究没有对照，且纳入的患者很少。最近，已经进行了双盲对照研究，比较了丙咪嗪、地昔帕明、阿米替林、苯乙肼和安慰剂。已发现总体疗效，但改善与相关症状（即焦虑和抑郁）的关系比与PTSD的核心症状的关系更密切。
