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柠檬香蜂草(L.)在心理健康方面的临床疗效和耐受性:综述。

Clinical Efficacy and Tolerability of Lemon Balm ( L.) in Psychological Well-Being: A Review.

机构信息

School of Psychology & Clinical Language Sciences, University of Reading, Earley Gate, Whiteknights Road, Reading RG6 6ES, UK.

Givaudan France Naturals, 250 rue Pierre Bayle, BP 81218, 84911 Avignon, France.

出版信息

Nutrients. 2024 Oct 18;16(20):3545. doi: 10.3390/nu16203545.

DOI:10.3390/nu16203545
PMID:39458539
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11510126/
Abstract

BACKGROUND

There is renewed interest in the use of ancient herbal remedies for their potential health benefits, particularly in the psychological domain. One herb that is receiving growing attention is lemon balm ( L.) which has received considerable interest for its influence on the brain. Lemon balm boasts an array of phytochemicals, including rosmarinic acid, citral, oleanolic acid, and ursolic acid, which are believed to underpin these effects on psychological well-being. Pharmacological evidence from animal and cellular work reveals that lemon balm and its components may modulate several brain signalling pathways, including GABAergic, cholinergic, and serotonergic systems.

RESULTS/CONCLUSIONS: Although further robust randomised controlled trials using lemon balm are required, existing research indicates that lemon balm holds promise as a calming agent exhibiting both anxiolytic and anti-depressant properties and can elicit cognitive and sleep-quality enhancement.

摘要

背景

由于其潜在的健康益处,特别是在心理领域,人们对使用古老的草药疗法重新产生了兴趣。一种受到越来越多关注的草药是柠檬香脂(L.),因为它对大脑的影响而引起了广泛关注。柠檬香脂含有多种植物化学物质,包括迷迭香酸、柠檬醛、齐墩果酸和熊果酸,这些物质被认为是其对心理健康产生影响的基础。动物和细胞研究的药理学证据表明,柠檬香脂及其成分可能调节几种大脑信号通路,包括 GABA 能、胆碱能和 5-羟色胺能系统。

结果/结论:尽管还需要使用柠檬香脂进行更多强有力的随机对照试验,但现有研究表明,柠檬香脂具有作为镇静剂的潜力,表现出抗焦虑和抗抑郁特性,并能增强认知和睡眠质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737c/11510126/9045d0a73a5f/nutrients-16-03545-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737c/11510126/9045d0a73a5f/nutrients-16-03545-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737c/11510126/9045d0a73a5f/nutrients-16-03545-g001.jpg

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