Creteanu Andreea, Lungu Claudiu N, Lungu Mirela
Department of Pharmaceutical Technology, University of Medicine and Pharmacy Grigore T Popa, 700115 Iași, Romania.
Department of Functional and Morphological Science, Faculty of Medicine and Pharmacy, Dunarea de Jos University, 800010 Galati, Romania.
Pharmaceuticals (Basel). 2024 Oct 21;17(10):1406. doi: 10.3390/ph17101406.
LIG is a biopolymer found in vascular plant cell walls that is created by networks of hydroxylated and methoxylated phenylpropane that are randomly crosslinked. Plant cell walls contain LIG, a biopolymer with significant potential for usage in modern industrial and pharmaceutical applications. It is a renewable raw resource. The plant is mechanically protected by this substance, which may increase its durability. Because it has antibacterial and antioxidant qualities, LIG also shields plants from biological and chemical challenges from the outside world. Researchers have done a great deal of work to create new materials and substances based on LIG. Numerous applications, including those involving antibacterial agents, antioxidant additives, UV protection agents, hydrogel-forming molecules, nanoparticles, and solid dosage forms, have been made with this biopolymer.
For this review, a consistent literature screening using the Pubmed database from 2019-2024 has been performed.
The results showed that there is an increase in interest in lignin as an adaptable biomolecule. The most recent studies are focused on the biosynthesis and antimicrobial properties of lignin-derived molecules. Also, the use of lignin in conjunction with nanostructures is actively explored.
Overall, lignin is a versatile molecule with multiple uses in industry and medical science.
木质素是一种存在于维管植物细胞壁中的生物聚合物，由羟基化和甲氧基化苯丙烷网络随机交联而成。植物细胞壁含有木质素，这种生物聚合物在现代工业和制药应用中具有巨大的应用潜力。它是一种可再生的原材料。这种物质对植物起到机械保护作用，可能会增强其耐久性。由于木质素具有抗菌和抗氧化特性，它还能保护植物免受外界生物和化学挑战。研究人员为基于木质素创造新材料和物质做了大量工作。这种生物聚合物已经有了许多应用，包括抗菌剂、抗氧化添加剂、紫外线防护剂、水凝胶形成分子、纳米颗粒和固体剂型等方面的应用。
在本次综述中，我们使用2019年至2024年的PubMed数据库进行了一致的文献筛选。
结果表明，人们对木质素作为一种适应性强的生物分子的兴趣有所增加。最新研究集中在木质素衍生分子的生物合成和抗菌特性上。此外，还积极探索木质素与纳米结构的联合使用。
总体而言，木质素是一种多功能分子，在工业和医学科学中有多种用途。
