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影响土耳其阻塞性睡眠呼吸暂停患者日常功能的因素。

Factors Affecting Daily Functioning in Turkish Patients with Obstructive Sleep Apnea.

机构信息

Department of Biostatistics and Medical Informatics, Faculty of Medicine, Duzce University, 81620 Duzce, Turkey.

Department of Chest Diseases, Faculty of Medicine, Duzce University, 81620 Duzce, Turkey.

出版信息

Medicina (Kaunas). 2024 Oct 9;60(10):1652. doi: 10.3390/medicina60101652.

Abstract

This study aims to examine the factors affecting the daily functioning of patients with obstructive sleep apnea (OSA). In addition to the polysomnography records of 361 patients, participants completed the Turkish FOSQ-10 (Functional Outcomes of Sleep-10), Medical Outcome Survey Short Form-12, Epworth Sleepiness Scale (ESS), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). First, the psychometrics properties of the Turkish FOSQ-10 were evaluated. Then, factors affecting daily functioning were examined through univariate and multivariate analyses. Of all participants, 68.7% ( = 248) were male, and the average age was 47.94 ± 11.08. According to the OSA category, 23% = 83) were mild, 22.7% ( = 82) were moderate, 45.2% ( = 163) were severe, and 9.1% = 33) were OSA negative. The Turkish FOSQ-10 was found to be a valid and reliable scale through validity and reliability analyses. The moderate and severe OSA patients had different FOSQ-10 Total scores compared to the negative OSA group. Daily functioning was positively associated with overall quality of life while inversely associated with depression, being anxious, and daytime sleepiness in OSA patients. In a multiple regression model, BDI, mental component summary-12, physical component summary-12, and ESS scores were significantly related to the FOSQ-10 Total score in OSA patients ( < 0.05). The daily functioning of moderate and severe OSA patients was worse than that of the negative OSA group. Depression, quality of life, and daytime sleepiness were simultaneously important variables associated with daily functioning in OSA patients.

摘要

本研究旨在探讨影响阻塞性睡眠呼吸暂停(OSA)患者日常功能的因素。除了 361 名患者的多导睡眠图记录外,参与者还完成了土耳其 FOSQ-10(睡眠 10 项功能结果)、医疗结果调查简表 12 项(Medical Outcome Survey Short Form-12)、Epworth 嗜睡量表(Epworth Sleepiness Scale,ESS)、贝克抑郁量表(Beck Depression Inventory,BDI)和贝克焦虑量表(Beck Anxiety Inventory,BAI)。首先,评估了土耳其 FOSQ-10 的心理测量学特性。然后,通过单变量和多变量分析检查影响日常功能的因素。所有参与者中,68.7%(=248)为男性,平均年龄为 47.94±11.08 岁。根据 OSA 类别,23%(=83)为轻度,22.7%(=82)为中度,45.2%(=163)为重度,9.1%(=33)为 OSA 阴性。通过效度和信度分析,发现土耳其 FOSQ-10 是一个有效且可靠的量表。与 OSA 阴性组相比,中重度 OSA 患者的 FOSQ-10 总分存在差异。在 OSA 患者中,日常功能与整体生活质量呈正相关,与抑郁、焦虑和白天嗜睡呈负相关。在多元回归模型中,BDI、12 项心理成分简明量表、12 项生理成分简明量表和 ESS 评分与 OSA 患者的 FOSQ-10 总分显著相关(<0.05)。中重度 OSA 患者的日常功能较 OSA 阴性组差。抑郁、生活质量和白天嗜睡是 OSA 患者日常功能的重要相关变量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1831/11509515/03b120905d86/medicina-60-01652-g001.jpg

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