阻塞性睡眠呼吸暂停患者的焦虑和抑郁相关性：系统评价和荟萃分析。
Association of Anxiety and Depression in Obstructive Sleep Apnea Patients: A Systematic Review and Meta-Analysis.
机构信息
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Maternal/Child Sciences (DINOGMI), University of Genoa, Genoa, Italy.
Department of Health Sciences, University of Genoa, Genoa, Italy.
出版信息
Behav Sleep Med. 2020 Jan-Feb;18(1):35-57. doi: 10.1080/15402002.2018.1545649. Epub 2018 Nov 19.
: Obstructive sleep apnea (OSA) has been associated with mental disorders, but the strength of this association is unknown. The aim of our study was to investigate the association among OSA, depression, and anxiety in adults and to quantitatively summarize the results. : A literature search in Medline, PubMed, PsycInfo, Scopus, and Web of Science was conducted. Seventy-three articles were selected for study. : The pooled prevalence of depressive and anxious symptoms in OSA patients was 35% (95% CI, 28-41%) and 32% (95% CI, 22-42%), respectively. : The association between OSA, anxiety, and depression indicates the value of an early diagnosis and personalized treatment of OSA to improve mental disorders conditioning compliance to therapy. These conditions share a probably bidirectional relationship.
阻塞性睡眠呼吸暂停（OSA）与精神障碍有关，但这种关联的强度尚不清楚。我们的研究目的是调查成人中 OSA、抑郁和焦虑之间的关联，并对结果进行定量总结。
我们在 Medline、PubMed、PsycInfo、Scopus 和 Web of Science 中进行了文献检索。选择了 73 篇文章进行研究。
OSA 患者抑郁和焦虑症状的合并患病率分别为 35%（95%CI，28-41%）和 32%（95%CI，22-42%）。
OSA、焦虑和抑郁之间的关联表明，早期诊断和个性化治疗 OSA 以改善精神障碍对治疗的依从性具有重要价值。这些情况可能存在双向关系。
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