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肌少症对接受标准康复治疗方案的急性脑卒中患者功能恢复的影响。

Effect of Sarcopenia on Functional Recovery in Acute Stroke Patients Admitted for Standard Rehabilitation Program.

机构信息

Department of Physical Therapy, Graduate School, Nambu University, Gwangju 62271, Republic of Korea.

Rehabilitation Center, Gwangju 365 Rehabilitation Hospital, Gwangju 62232, Republic of Korea.

出版信息

Medicina (Kaunas). 2024 Oct 20;60(10):1716. doi: 10.3390/medicina60101716.

Abstract

: Sarcopenia is a significant concern in stroke rehabilitation, with a high prevalence reported in acute stroke patients. This study examines the effect of sarcopenia on rehabilitation outcomes in acute stroke patients. : This study was conducted with acute stroke patients admitted within 90 days of onset to the rehabilitation hospital. Participants were divided into a stroke with sarcopenia group and a stroke without sarcopenia group. Evaluations were conducted at baseline, 4 weeks, and 8 weeks, including the following assessments: manual muscle testing (MMT), Berg Balance Scale (BBS), functional ambulation category (FAC), and Modified Barthel Index (MBI). Both groups received an identical rehabilitation program for 8 weeks. : Significant within-group improvements were observed in both groups across all measures ( < 0.05). However, the stroke with sarcopenia group showed significantly less improvement in MMT, BBS, FAC, and MBI compared to the stroke without sarcopenia group at both 4 and 8 weeks ( < 0.05). : These results underscore the significant impact of sarcopenia on functional recovery in stroke patients, despite both groups receiving identical rehabilitation programs. The presence of sarcopenia was a critical predictor of poorer outcomes in muscle strength, balance, ambulation, and activities of daily living. Given these findings, specific rehabilitation strategies targeting sarcopenia are needed to improve recovery in stroke patients. Future research should include larger sample sizes, longer follow-ups, and sarcopenic patient-specific rehabilitation programs.

摘要

肌肉减少症是中风康复中的一个重要问题,急性中风患者中发病率较高。本研究探讨了肌肉减少症对急性中风患者康复结局的影响。

本研究纳入了发病后 90 天内入住康复医院的急性中风患者。将参与者分为伴有肌肉减少症的中风组和不伴有肌肉减少症的中风组。在基线、4 周和 8 周时进行评估,包括以下评估:手法肌肉测试(MMT)、伯格平衡量表(BBS)、功能性步行分类(FAC)和改良巴氏指数(MBI)。两组均接受 8 周的相同康复计划。

两组在所有指标上均有显著的组内改善(<0.05)。然而,与不伴有肌肉减少症的中风组相比,伴有肌肉减少症的中风组在 4 周和 8 周时的 MMT、BBS、FAC 和 MBI 改善明显较少(<0.05)。

这些结果强调了肌肉减少症对中风患者功能恢复的重大影响,尽管两组均接受相同的康复计划。肌肉减少症的存在是肌肉力量、平衡、步行和日常生活活动能力较差的重要预测因素。鉴于这些发现,需要针对肌肉减少症的特定康复策略来改善中风患者的康复。未来的研究应包括更大的样本量、更长的随访时间和针对肌肉减少症患者的特定康复计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a642/11509405/1f2f9a0b3d96/medicina-60-01716-g001.jpg

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