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一项针对患有肌肉减少症的中风后患者的社区抗阻训练运动:在一项多中心随机对照试验中衔接机构康复和社区康复

A Community-Based Resistance Training Exercise for Post-Stroke Patients with Sarcopenia: Bridging Institutional and Community-Based Rehabilitation in a Multicenter, Randomized Controlled Trial.

作者信息

Kang Dongheon, Park Jiyoung

机构信息

Department of Healthcare and Public Health Research, National Rehabilitation Center, Ministry of Health and Welfare, Seoul 01022, Republic of Korea.

Department of Safety and Health, Wonkwang University, Iksan 54538, Republic of Korea.

出版信息

Life (Basel). 2025 May 7;15(5):748. doi: 10.3390/life15050748.

Abstract

Sarcopenia is a prevalent and debilitating condition among stroke survivors, characterized by the progressive loss of muscle mass and function. This multicenter, randomized controlled trial aims to evaluate the effects of a community-based high-speed power training (HSPT) program tailored for individuals with post-stroke sarcopenia. The intervention bridges the gap between hospital-based rehabilitation and long-term community reintegration by offering physician-supervised, progressive resistance training sessions conducted twice weekly for eight weeks. Participants are assessed on muscle strength, physical performance, balance, body composition, and gait before and after the intervention. The study utilizes validated tools such as handgrip dynamometry, dual-energy X-ray absorptiometry (DXA), short physical performance battery (SPPB), and timed up and go (TUG) to comprehensively evaluate outcomes. Through stratified randomization and a double-blind design, the trial seeks to minimize bias and maximize clinical relevance. The results from this protocol are expected to inform evidence-based guidelines for stroke rehabilitation and support scalable community-based exercise programs aimed at improving functional recovery and quality of life in this population.

摘要

肌肉减少症是中风幸存者中普遍存在且使人衰弱的一种病症,其特征是肌肉质量和功能逐渐丧失。这项多中心随机对照试验旨在评估一项为中风后肌肉减少症患者量身定制的社区高速力量训练(HSPT)计划的效果。该干预措施通过提供由医生监督的、每周两次、为期八周的渐进性抗阻训练课程,弥合了基于医院的康复与长期社区重新融入之间的差距。在干预前后,对参与者的肌肉力量、身体表现、平衡能力、身体成分和步态进行评估。该研究使用了诸如握力计、双能X线吸收法(DXA)、简短身体功能测试(SPPB)和计时起立行走测试(TUG)等经过验证的工具来全面评估结果。通过分层随机化和双盲设计,该试验旨在尽量减少偏差并最大化临床相关性。该方案的结果有望为中风康复的循证指南提供依据,并支持旨在改善该人群功能恢复和生活质量的可扩展的社区运动计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9914/12113312/83fec67a76be/life-15-00748-g001.jpg

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