Burkhanbayeva Tolkynay, Ukhov Arthur, Assylbekova Dina, Mussina Zukhra, Kurzina Irina, Abilkasova Sandugash, Bakibaev Abdigali, Issabayeva Manar, Yerkassov Rakhmetulla, Shaikhova Zhanat
Chemistry Department, Faculty of Natural Sciences, L. N. Gumilyov Eurasian National University, Astana 010000, Kazakhstan.
Chemistry Department, National Research Tomsk State University, Arkady Ivanov St. 49, 634028 Tomsk, Russia.
Materials (Basel). 2024 Oct 12;17(20):4995. doi: 10.3390/ma17204995.
In this work, composite materials were obtained for the first time using various methods and the dependences of the resulting surface morphologies were investigated. This involves modifying the surface with cucurbit[n]urils, which are highly promising macrocyclic compounds. The process includes applying cucurbit[6]uril to the hydroxyapatite surface in water using different modification techniques. The first method involved precipitating a dispersion of in undissolved form in water. The second method involved using fully dissolved in deionized water, after which the composite materials were dried to constant weight. The third method involved several steps: first, was dissolved in deionized water, then, upon heating, a dispersion of was formed on the surface of . The fourth method involved using ultrasonic treatment. All four methods yielded materials with different surface morphologies, which were studied and characterized using techniques such as infrared (IR) spectroscopy and scanning electron microscopy (SEM). Based on these results, it is possible to vary the properties and surface morphology of the obtained materials. Depending on the method of applying to the surface and inside the scaffold, it is possible to adjust the composition and structure of the target composite materials. The methods for applying to the hydroxyapatite surface enhance its versatility and compatibility with the body's environment, which is crucial for developing new functional composite materials. This includes leveraging supramolecular systems based on the family. The obtained results can be used to model the processes of obtaining biocomposite materials, as well as to predict the properties of future materials with biological activity.
在这项工作中，首次使用各种方法获得了复合材料，并研究了所得表面形态的依赖性。这涉及用葫芦[n]脲对表面进行改性，葫芦[n]脲是非常有前景的大环化合物。该过程包括使用不同的改性技术将葫芦[6]脲应用于水中的羟基磷灰石表面。第一种方法是将以未溶解形式沉淀在水中。第二种方法是使用在去离子水中完全溶解的，之后将复合材料干燥至恒重。第三种方法包括几个步骤：首先，将溶解在去离子水中，然后加热，在表面形成的分散体。第四种方法是使用超声处理。所有四种方法都产生了具有不同表面形态的材料，使用红外（IR）光谱和扫描电子显微镜（SEM）等技术对其进行了研究和表征。基于这些结果，可以改变所得材料的性能和表面形态。根据将应用于支架表面和内部的方法，可以调整目标复合材料的组成和结构。将应用于羟基磷灰石表面的方法增强了其多功能性以及与人体环境的兼容性，这对于开发新型功能复合材料至关重要。这包括利用基于家族的超分子系统。所得结果可用于模拟生物复合材料的制备过程，以及预测具有生物活性的未来材料的性能。
