Calderon Chrystal, Ramnarine Devindra, Knight Patrick, Ramcharan Robert
Eric Williams Medical Sciences Complex, Mount Hope, Trinidad and Tobago.
Eric Williams Medical Sciences Complex, Mount Hope, Trinidad and Tobago.
Int J Surg Case Rep. 2024 Dec;125:110514. doi: 10.1016/j.ijscr.2024.110514. Epub 2024 Oct 24.
Posterior reversible encephalopathy syndrome (PRES) is a rare complication following surgical intervention, with varied neurological manifestations. The inherent pathophysiology is diverse and risk factors include certain medical co-morbidities.
A previously well 24-year-old female, presented with signs of elevated intracranial pressure, with further investigations highlighting a posterior fossa tumor. She was scheduled for resection of this intracranial lesion and the surgical procedure was uneventful. However, moderate but significant labile increases in blood pressures were noted intra- and post- operatively. Following surgery, a clinical presentation of limb weakness and gaze deviation was observed, leading to investigative imaging demonstrating PRES. She was treated expeditiously by a multi-disciplinary team. There was complete resolution of her symptomology once the underlying cause was identified.
PRES is not a typical complication of a neurosurgical patient. Moreso, in a young patient without any medical comorbidities. Deviation of her blood pressures from the normal lead to the formation of vasogenic edema along the cerebral hemispheres. The manifestation of this clinically made it arduous to pinpoint a definitive diagnosis. With the aid of different specialists, a diagnosis was clenched, and treatment was successfully implemented.
The major learning point of this case history is the recognition of alterations from a patient's baseline vital signs (blood pressure) during and following surgical procedures. Additionally, the resultant consequences of these deviations, which may manifest as rare neurological conditions, such as PRES. The importance of a multi-disciplinary team in the management of this case was paramount.
后部可逆性脑病综合征(PRES)是手术干预后一种罕见的并发症,具有多种神经学表现。其内在病理生理学是多样的,危险因素包括某些合并症。
一名既往健康的24岁女性,出现颅内压升高的体征,进一步检查发现后颅窝肿瘤。她被安排切除该颅内病变,手术过程顺利。然而,术中及术后均注意到血压出现中度但显著的不稳定升高。术后,观察到患者出现肢体无力和凝视偏斜的临床表现,影像学检查显示为PRES。一个多学科团队迅速对她进行了治疗。一旦确定了潜在病因,她的症状就完全消失了。
PRES并非神经外科患者的典型并发症。更确切地说,是在一名无任何合并症的年轻患者中出现。她的血压偏离正常导致沿大脑半球形成血管源性水肿。这种临床表现使得难以明确诊断。在不同专科医生的帮助下,做出了诊断并成功实施了治疗。
该病例的主要经验教训是认识到手术期间及术后患者基线生命体征(血压)的变化。此外,这些偏差可能导致罕见的神经疾病,如PRES。多学科团队在该病例管理中的重要性至关重要。