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Regulation of lung endothelial permeability by NEK kinases.NEK激酶对肺内皮细胞通透性的调节
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NEK-mediated barrier regulation.Nek 介导的屏障调节。
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Involvement of NEK2 and NEK9 in LPS - induced endothelial barrier dysfunction.NEK2 和 NEK9 在内毒素诱导的内皮屏障功能障碍中的作用。
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Induction of the NEK family of kinases in the lungs of mice subjected to cecal ligation and puncture model of sepsis.在盲肠结扎和穿刺脓毒症模型的小鼠肺部诱导 NEK 家族激酶。
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Endothelial Functions.内皮功能
Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):e108-e114. doi: 10.1161/ATVBAHA.117.309813.
7
Emerging roles of SIRT1 in vascular endothelial homeostasis.SIRT1在血管内皮稳态中的新作用。
Cell Cycle. 2008 Jul 15;7(14):2117-22. doi: 10.4161/cc.7.14.6267. Epub 2008 May 8.
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HSP27 phosphorylation protects against endothelial barrier dysfunction under burn serum challenge.热休克蛋白27磷酸化可在烧伤血清刺激下预防内皮屏障功能障碍。
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Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation.在稳态和炎症过程中不同血管床内皮细胞的异质性。
Elife. 2020 Jan 16;9:e51413. doi: 10.7554/eLife.51413.
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Targets for pharmacological intervention of endothelial hyperpermeability and barrier function.内皮细胞高通透性和屏障功能的药理学干预靶点。
Vascul Pharmacol. 2002 Nov;39(4-5):257-72. doi: 10.1016/s1537-1891(03)00014-4.
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Pasireotide Exerts Anti-Inflammatory Effects in the Endothelium.帕西瑞肽在内皮细胞中发挥抗炎作用。
J Biochem Mol Toxicol. 2025 May;39(5):e70306. doi: 10.1002/jbt.70306.
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NEK2 inhibition alleviates lipopolysaccharide-induced endothelial injury.NEK2抑制可减轻脂多糖诱导的内皮损伤。
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NEK kinases in cell cycle regulation, DNA damage response, and cancer progression.NEK激酶在细胞周期调控、DNA损伤反应及癌症进展中的作用
Tissue Cell. 2025 Jun;94:102811. doi: 10.1016/j.tice.2025.102811. Epub 2025 Feb 28.
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Ceapin-A7 suppresses the protective effects of Octreotide in human and bovine lung endothelial cells.Ceapin-A7抑制奥曲肽对人及牛肺内皮细胞的保护作用。
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Protective Activities of Growth Hormone-Releasing Hormone Antagonists against Toxin-Induced Endothelial Injury.生长激素释放激素拮抗剂对毒素诱导的内皮损伤的保护作用。
Endocrines. 2024 Mar;5(1):116-123. doi: 10.3390/endocrines5010008. Epub 2024 Mar 18.
2
β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells.β-连环蛋白的周转率受 Nek10 介导的酪氨酸磷酸化在 A549 肺腺癌细胞中的调控。
Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2300606121. doi: 10.1073/pnas.2300606121. Epub 2024 Apr 29.
3
Involvement of NEK2 and NEK9 in LPS - induced endothelial barrier dysfunction.NEK2 和 NEK9 在内毒素诱导的内皮屏障功能障碍中的作用。
Microvasc Res. 2024 Mar;152:104651. doi: 10.1016/j.mvr.2023.104651. Epub 2024 Jan 2.
4
Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophy.富克斯角膜内皮营养不良中的非凋亡性调节性细胞死亡。
Regen Ther. 2023 Nov 10;24:592-601. doi: 10.1016/j.reth.2023.11.001. eCollection 2023 Dec.
5
Activating transcription factor 6 in the endothelial context.在内皮细胞环境中激活转录因子6
Pulm Pharmacol Ther. 2023 Jun;80:102216. doi: 10.1016/j.pupt.2023.102216. Epub 2023 Apr 28.
6
Growth Hormone-Releasing Hormone in Endothelial Inflammation.生长激素释放激素与血管内皮炎症
Endocrinology. 2022 Dec 19;164(2). doi: 10.1210/endocr/bqac209.
7
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart.NIMA 相关激酶 9 调节心脏中必需肌球蛋白轻链的磷酸化。
Nat Commun. 2022 Oct 20;13(1):6209. doi: 10.1038/s41467-022-33658-2.
8
Analysis of the effect of NEKs on the prognosis of patients with non-small-cell lung carcinoma based on bioinformatics.基于生物信息学分析 NEKs 对非小细胞肺癌患者预后的影响。
Sci Rep. 2022 Feb 1;12(1):1705. doi: 10.1038/s41598-022-05728-4.
9
The NEK family of serine/threonine kinases as a biomarker for cancer.丝氨酸/苏氨酸激酶的NEK家族作为癌症的生物标志物。
Clin Exp Med. 2023 Feb;23(1):17-30. doi: 10.1007/s10238-021-00782-0. Epub 2022 Jan 17.
10
Circular RNA NEK6 contributes to the development of non-small-cell lung cancer by competitively binding with miR-382-5p to elevate BCAS2 expression at post-transcriptional level.环状 RNA NEK6 通过与 miR-382-5p 竞争结合来提高 BCAS2 表达水平，从而促进非小细胞肺癌的发展。
BMC Pulm Med. 2021 Oct 18;21(1):325. doi: 10.1186/s12890-021-01617-0.
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