Post graduate student, Prosthodontics, Department of Prosthodontics, Sri Ramaswamy Memorial Dental College, Bharathi Salai,Ramapuram, Chennai, Tamil Nadu, India.
Department of Prosthodontics, Sri Ramaswamy Memorial Dental College, Bharathi Salai, Ramapuram, Chennai, Tamil Nadu, India.
BMC Oral Health. 2024 Oct 26;24(1):1300. doi: 10.1186/s12903-024-05086-9.
Current denture base resins lack adequate strength and antimicrobial properties, necessitating the exploration of alternative solutions. The purpose of this study was to evaluate the effects of curcumin incorporation on the physico-mechanical properties of heat-cured denture base resin, filling a gap in the literature regarding this correlation.
Heat-cured denture base resin was supplemented with increasing concentrations of curcumin (CR). Groups were designated as CR-0 (0%), CR-0.05 (0.05%), CR-0.10 (0.10%), CR-0.50 (0.50%), and CR-1 (1%), based on the increasing concentrations of curcumin incorporated into the material. Physico-mechanical properties, including flexural strength, surface roughness, fracture toughness, impact strength, and color difference, were evaluated following the testing standards. Statistical analysis involved Kruskal-Wallis ANOVA followed by Dunn's test for multiple comparisons, with significance set at P ≤ 0.05 and Bonferroni's correction applied to p-values.
Flexural strength peaked at 153.80 MPa in the CR-0.10 group, while surface roughness was lowest at 0.14 micrometers in the CR-0.50 group. Fracture toughness reached its highest value at 1.80 kJ/m^2 in the CR-0.05 group, and impact strength was greatest at 6.52 Joules in the CR-0.05 group. Additionally, color difference was least pronounced in the CR-0.50 group. Flexural strength, surface roughness, fracture toughness, impact strength, and color difference varied significantly among the control group and different curcumin concentrations (P < 0.05).
Incorporating curcumin into denture base resin alters both optical and mechanical properties. Further research is required to validate the findings and determine the optimal curcumin concentration without compromising the material efficacy.
目前的义齿基托树脂缺乏足够的强度和抗菌性能，因此需要探索替代解决方案。本研究的目的是评估姜黄素的掺入对热固化义齿基托树脂的物理机械性能的影响，填补了关于这种相关性的文献空白。
热固化义齿基托树脂中添加了不同浓度的姜黄素（CR）。根据材料中掺入的姜黄素浓度的增加，将各组分别命名为 CR-0（0%）、CR-0.05（0.05%）、CR-0.10（0.10%）、CR-0.50（0.50%）和 CR-1（1%）。根据测试标准，评估物理机械性能，包括弯曲强度、表面粗糙度、断裂韧性、冲击强度和色差。统计分析采用 Kruskal-Wallis ANOVA 检验，然后进行多重比较的 Dunn 检验，显著性水平设为 P≤0.05，并对 p 值进行 Bonferroni 校正。
在 CR-0.10 组中，弯曲强度达到 153.80 MPa 的峰值，而在 CR-0.50 组中表面粗糙度最低为 0.14 微米。在 CR-0.05 组中，断裂韧性达到 1.80 kJ/m^2 的最大值，在 CR-0.05 组中冲击强度达到 6.52 焦耳的最大值。此外，在 CR-0.50 组中色差最小。弯曲强度、表面粗糙度、断裂韧性、冲击强度和色差在对照组和不同姜黄素浓度之间差异有统计学意义（P<0.05）。
将姜黄素掺入义齿基托树脂会改变光学和机械性能。需要进一步的研究来验证这些发现，并确定在不影响材料功效的情况下最佳的姜黄素浓度。
