Pediatric Surgery Department, IRCCS, Istituto Giannina Gaslini, Genoa, Italy.
DINOGMI, University of Genoa, Genoa, Italy.
J Laparoendosc Adv Surg Tech A. 2024 Nov;34(11):1044-1050. doi: 10.1089/lap.2023.0382. Epub 2024 Oct 28.
Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis (IPAA) is the gold standard surgical treatment for patients with ulcerative colitis (UC) unresponsive to medical therapy and those with familial adenomatous polyposis. Robotic IPAA is a safe and feasible option for the surgical treatment of UC in children. The feasibility of IPAA without ileostomy has been demonstrated in adult in the modified two-stage approach. The aim of the study was to examine feasibility, outcomes, and complications of robotic modified two-stage approach for RPC with IPAA in pediatric patients comparing it with robotic three-stage approach. All patients aged 4-18 years who underwent operative treatment for medically refractory UC were included. Demographic and clinical features, age at colectomy and at reconstructive surgery, intraoperative details and complications, and postoperative outcomes were analyzed. Thirteen patients were included in the study (6 males, 7 females). Ileostomy was fashioned in 8 patients at the time of RPC and IPAA (Group 1); in 5 patients the bowel continuity was reintegrated at the time of IPAA (Group 2). No intraoperative complications and no conversions were recorded. One patient of Group 1 had a postoperative pouch complication. The 5 patients who underwent a two-stage procedure did not show short-term complications. No statistical differences were found between the groups in short-term ( = .48) and long-term complications ( = .07). Modified two-stage IPAA is a safe and feasible option in pediatric patients with UC, and RALS offers advantages over other techniques for the precision of rectal dissection and ileo-anal anastomosis.
回肠贮袋肛管吻合术(IPAA)联合直肠切除术是对药物治疗无效的溃疡性结肠炎(UC)患者和家族性腺瘤性息肉病患者的金标准手术治疗方法。机器人 IPAA 是儿童 UC 手术治疗的一种安全可行的选择。在改良两阶段方法中,已经证明无回肠造口术的 IPAA 是可行的。本研究的目的是比较机器人改良两阶段 IPAA 与机器人三阶段 IPAA 在儿童患者中的可行性、结果和并发症。所有接受手术治疗的 4-18 岁药物难治性 UC 患者均被纳入研究。分析了人口统计学和临床特征、结肠切除术和重建手术的年龄、术中细节和并发症以及术后结果。本研究纳入了 13 名患者(6 名男性,7 名女性)。8 名患者在直肠切除术和 IPAA 时行回肠造口术(第 1 组);5 名患者在 IPAA 时重建肠连续性(第 2 组)。未记录到术中并发症和转换。第 1 组中有 1 例患者术后出现储袋并发症。接受两阶段手术的 5 例患者未出现短期并发症。两组间短期( =.48)和长期并发症( =.07)无统计学差异。改良两阶段 IPAA 是儿童 UC 患者的一种安全可行的选择,机器人辅助腹腔镜手术在直肠解剖和回肠肛管吻合术的精确性方面优于其他技术。