Alomari Ahmad, Althunibat Ismail, Obri Mark S, Curran John, Aldroubi Basel, Davis William, Pompa Robert
Internal Medicine, Henry Ford Health System, Detroit, USA.
Internal Medicine, Saint Michael's Medical Center, Newark, USA.
Cureus. 2024 Sep 27;16(9):e70329. doi: 10.7759/cureus.70329. eCollection 2024 Sep.
Metastatic seminoma to the pancreas is exceedingly rare, with few reported cases in medical literature. We present a case of a 66-year-old male, six years post-remission from testicular seminoma, who presented with obstructive jaundice and a pancreatic mass mimicking primary malignancy. Diagnostic workup including endoscopic ultrasound-guided biopsy confirmed metastatic seminoma. He underwent successful treatment with four cycles of cisplatin and etoposide, achieving complete remission. This case underscores the diagnostic challenge of pancreatic metastases and emphasizes the role of biopsy in guiding appropriate management. Awareness of such presentations is crucial for timely intervention and improved patient outcomes.
胰腺转移性精原细胞瘤极为罕见，医学文献中报道的病例很少。我们报告一例66岁男性，睾丸精原细胞瘤缓解后6年，出现梗阻性黄疸和疑似原发性恶性肿瘤的胰腺肿块。包括内镜超声引导下活检在内的诊断检查确诊为转移性精原细胞瘤。他接受了四个周期的顺铂和依托泊苷治疗并取得成功，实现了完全缓解。该病例强调了胰腺转移瘤的诊断挑战，并强调了活检在指导适当治疗中的作用。认识到这种表现对于及时干预和改善患者预后至关重要。
