Leton Noah
Physiology, Neuroscience and Behavioural Sciences, St. George's University, St. George's, GRD.
Cureus. 2024 Sep 27;16(9):e70313. doi: 10.7759/cureus.70313. eCollection 2024 Sep.
The insidious grip of substance use disorders (SUDs) manifests as a ubiquitous public health crisis, indiscriminately affecting individuals across the spectrum of age, gender, and socioeconomic status. While advancements in treatment offer a glimmer of hope, millions continue to grapple with the debilitating physical, psychological, and social consequences of addiction, particularly those involving alcohol and opioids. This crisis is further exacerbated by the alarming rise of SUDs among older adults. As the global population undergoes a process of demographic senescence, the escalating prevalence of SUDs in this demographic underscores the urgent need for nuanced interventions. This review explores the therapeutic landscape for managing SUDs in older adults, evaluating pharmacological and non-pharmacological treatment modalities. A detailed literature search was conducted using databases like PubMed, Google Scholar, and Scopus, and studies were selected based on their relevance to therapeutic interventions for older adults with SUDs, encompassing pharmacological and non-pharmacological modalities. The synthesized results provide an extensive overview of contemporary therapeutic approaches. The findings indicate that pharmacological interventions demonstrate varied effectiveness in managing opioid and alcohol use disorders, with each drug offering distinct benefits and limitations regarding safety, tolerability, and patient adherence. Non-pharmacological interventions provide critical psychological and social support, often requiring adaptations to meet elderly patients' needs effectively. Integrated care models, which combine pharmacological and non-pharmacological treatments, emerge as the most effective approach, addressing the comprehensive needs of elderly patients by leveraging multidisciplinary teams, centralized service access, and coordinated, patient-centered care. Implementing these models, however, requires overcoming significant resource and coordination challenges. Indeed, the confluence of a burgeoning geriatric population and escalating rates of SUDs necessitates the development and implementation of granular and integrated care protocols specifically designed for older adults. By employing such a targeted approach, optimism can be cultivated and the quality of life enhanced for this vulnerable and often overlooked segment of society. This ensures the fight against addiction extends its reach, leaving no one behind.
物质使用障碍(SUDs)的潜在影响呈现为一场普遍存在的公共卫生危机,不分年龄、性别和社会经济地位地影响着各个层面的个人。尽管治疗方面的进展带来了一线希望,但仍有数百万人继续与成瘾带来的身体、心理和社会层面的衰弱后果作斗争,尤其是那些涉及酒精和阿片类药物的成瘾问题。老年人中物质使用障碍惊人的增长进一步加剧了这场危机。随着全球人口步入老龄化进程,这一人群中物质使用障碍患病率的不断上升凸显了采取细致入微的干预措施的迫切需求。本综述探讨了针对老年人物质使用障碍的治疗前景,评估了药物和非药物治疗方式。使用PubMed、谷歌学术和Scopus等数据库进行了详细的文献检索,并根据其与老年物质使用障碍患者治疗干预措施的相关性选择了研究,涵盖药物和非药物治疗方式。综合结果提供了当代治疗方法的广泛概述。研究结果表明,药物干预在治疗阿片类药物和酒精使用障碍方面显示出不同的效果,每种药物在安全性、耐受性和患者依从性方面都有独特的益处和局限性。非药物干预提供了关键的心理和社会支持,通常需要进行调整以有效满足老年患者的需求。将药物和非药物治疗相结合的综合护理模式成为最有效的方法,通过利用多学科团队、集中的服务获取途径以及协调的、以患者为中心的护理来满足老年患者的全面需求。然而,实施这些模式需要克服重大的资源和协调挑战。事实上,老年人口的不断增长和物质使用障碍发生率的不断上升,使得必须制定和实施专门为老年人设计的详细且综合的护理方案。通过采用这种有针对性的方法,可以培养乐观情绪,并提高这一脆弱且常被忽视的社会群体的生活质量。这确保了与成瘾的斗争能够惠及所有人,不落下任何一个人。