Ina Emily A, Roberts Christopher C
Medicine, Osteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Neurosurgery, Broward Health, Fort Lauderdale, USA.
Cureus. 2024 Sep 26;16(9):e70284. doi: 10.7759/cureus.70284. eCollection 2024 Sep.
The formation of neural tube defects, such as a meningomyelocele, is often sporadic and more common in monozygotic twin gestations but can be associated with folic acid deficiency and rarely occurs in dizygotic twins. In this case report, we present dizygotic twins born in the United States with meningomyeloceles. In addition, their neural tube defects were complicated by hydrocephalus and decreased muscle tone and movement in the lower extremities. Repair of the meningomyeloceles occurred 48 hours after birth with neurosurgical intervention, and placement of ventriculoperitoneal shunts was performed two weeks later once the neonates were of appropriate weight. This case report presents a rare occurrence of dizygotic twins with concurrent meningomyeloceles requiring post-natal surgical intervention to improve quality of life and decrease fatal complications of neural tube defects.
神经管缺陷的形成，如脊髓脊膜膨出，通常是散发性的，在单卵双胎妊娠中更常见，但可能与叶酸缺乏有关，在双卵双胎中很少发生。在本病例报告中，我们介绍了在美国出生的患有脊髓脊膜膨出的双卵双胎。此外，他们的神经管缺陷合并脑积水以及下肢肌张力和运动减弱。出生后48小时进行了神经外科干预修复脊髓脊膜膨出，两周后，一旦新生儿体重合适，就进行了脑室腹腔分流术。本病例报告展示了罕见的双卵双胎同时患有脊髓脊膜膨出，需要产后手术干预以提高生活质量并减少神经管缺陷的致命并发症。
