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母亲体重与妊娠期糖尿病对儿童健康的影响:一项叙述性综述。

Maternal Weight and Gestational Diabetes Impacts on Child Health: A Narrative Review.

作者信息

Khandelwal Rahul, Meshram Revat J, Patel Ankita, Reddy Sneha, Manek Yogesh B

机构信息

Pediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 Sep 25;16(9):e70192. doi: 10.7759/cureus.70192. eCollection 2024 Sep.

Abstract

Maternal weight and gestational diabetes mellitus (GDM) have significant implications for both maternal and child health. This narrative review explores the intricate relationship between maternal pre-pregnancy weight, gestational weight gain, and GDM, focusing on their short- and long-term effects on child health outcomes. The review highlights evidence linking maternal obesity and GDM to increased risks of adverse outcomes in infants and children, such as macrosomia, neonatal hypoglycemia, childhood obesity, and metabolic disorders. It also discusses the intergenerational transmission of metabolic risk, underscoring the importance of early intervention and prevention strategies in maternal healthcare. Furthermore, the review emphasizes the need for tailored approaches to managing maternal weight and GDM to mitigate potential risks and improve health outcomes for future generations. Key recommendations include promoting healthy preconception weight, monitoring gestational weight gain, and enhancing postnatal follow-up for both mothers and children. This review underscores the critical role of maternal health in shaping the developmental trajectory of offspring and highlights opportunities for healthcare professionals to reduce the long-term impact of GDM on child health.

摘要

母亲体重与妊娠期糖尿病(GDM)对母婴健康都有重大影响。这篇叙述性综述探讨了母亲孕前体重、孕期体重增加与妊娠期糖尿病之间的复杂关系,重点关注它们对儿童健康结局的短期和长期影响。该综述强调了将母亲肥胖和妊娠期糖尿病与婴儿和儿童不良结局风险增加联系起来的证据,如巨大儿、新生儿低血糖、儿童肥胖和代谢紊乱。它还讨论了代谢风险的代际传递,强调了孕产妇保健中早期干预和预防策略的重要性。此外,该综述强调需要采取量身定制的方法来管理母亲体重和妊娠期糖尿病,以减轻潜在风险并改善后代的健康结局。主要建议包括促进孕前健康体重、监测孕期体重增加以及加强对母亲和儿童的产后随访。这篇综述强调了孕产妇健康在塑造后代发育轨迹中的关键作用,并突出了医疗保健专业人员减少妊娠期糖尿病对儿童健康长期影响的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c48d/11508815/1a2039b1122f/cureus-0016-00000070192-i01.jpg

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