Department of Biomedical sciences, College of Medicine, University of Zakho, Kurdistan Region, Iraq.
Department of Medical Lab Technology, Shekhan Technical College of Health, Duhok Polytechnic University, Duhok, Kurdistan Region, Iraq.
Arch Razi Inst. 2024 Apr 30;79(2):272-278. doi: 10.32592/ARI.2024.79.2.272. eCollection 2024 Apr.
is known to increase the risk of developing gastritis, peptic ulcer disease, gastric adenocarcinoma, and gastric lymphoma in adults across the globe. The present study aimed to determine the prevalence of H. pylori infection and its associated risk factors. This cross-sectional study was conducted among the adult population in Duhok Province, Kurdistan Region, Iraq. A total of 259 subjects over the age of 18 who visited the hospitals were included in the study from 2018 to 2020. An enzyme-linked immunosorbent assay was utilized to determine seropositivity. A standardized questionnaire was administered to all study participants through face-to-face interviews. The immunoglobulin G (IgG) antibody data were analyzed using the Chi-square test. The prevalence of anti- IgG antibody was present in 40.02% of adults. Among the studied variables, the following risk factors were significantly associated with the presence of anti IgG antibodies: male gender (<0.043), level of education (<0.025), history of gastrointestinal diseases (<0.001), smoking status (<0.001), and more siblings (<0.001). This study supports the hypothesis that infection in adults is highly related to poor hygiene and smoking status, low level of education, and crowded conditions. Therefore, in order to reduce the prevalence of infection among adults, it is crucial to implement effective strategies aimed at enhancing fundamental sanitary conditions, as well as improving educational and socioeconomic status.
已知在全球范围内,会增加成年人患胃炎、消化性溃疡病、胃腺癌和胃淋巴瘤的风险。本研究旨在确定幽门螺杆菌感染的流行率及其相关危险因素。这是一项在伊拉克库尔德地区杜胡克省进行的横断面研究。2018 年至 2020 年期间,从医院就诊的 259 名 18 岁以上的成年人中选取了本研究的对象。采用酶联免疫吸附测定法来确定血清阳性。通过面对面访谈,向所有研究对象发放了标准化问卷。使用卡方检验对免疫球蛋白 G(IgG)抗体数据进行分析。在成年人中,存在抗 IgG 抗体的比例为 40.02%。在所研究的变量中,以下危险因素与 IgG 抗体的存在显著相关:男性(<0.043)、教育水平(<0.025)、胃肠道疾病史(<0.001)、吸烟状况(<0.001)和兄弟姐妹较多(<0.001)。本研究支持了这样一种假设,即成年人中 感染与卫生条件差、吸烟状况、教育水平低和拥挤的环境密切相关。因此,为了降低成年人中 感染的流行率,实施旨在改善基本卫生条件以及教育和社会经济地位的有效策略至关重要。