Tay San San, Zhang Fuquan, Visperas Christine Alejandro, Koh Xuan Han, Lau Borisut, Neo Jin Rui Edmund
Department of Rehabilitation Medicine, Changi General Hospital, Singapore, Singapore.
Department of Health Services Research, Changi General Hospital, Singapore, Singapore.
Front Neurol. 2024 Oct 11;15:1415773. doi: 10.3389/fneur.2024.1415773. eCollection 2024.
To assess the feasibility and safety of conducting robot-mediated impairment training (RMIT) and robot-mediated task-specific training (RMTT). The device deployed is the Optimo Regen (OR), capable of delivering both impairment-oriented training and task-specific training.
This was a single-centre, randomized, single-blinded, two-arm, parallel group, controlled trial. Patients fulfilling criteria were randomized into either the RMIT or RMIT + RMTT group and provided with 20 h of robotic therapy on top of standard care.
A total of 4 patients were recruited, with 2 patients receiving treatment in each arm. The study was feasible, with a 66.7% enrolment rate, 75% completion rate, and 100% attendance for each intervention session. We achieved a 90% satisfaction rate with no serious adverse effects. All patients had improvement of motor power, Fugl-Meyer Assessment-Upper Extremity (FMA-UE), Functional Independence Measure (FIM), Hospital Anxiety and Depression Scale (HADS), and quality of life scores at 1 month. FIM continued to improve at 3 months post-commencement of intervention. There was relative ease of use of the device.
This trial is feasible. A full-scale study is warranted, to compare RMIT against RMTT, which is a novel application.
评估进行机器人介导的损伤训练（RMIT）和机器人介导的特定任务训练（RMTT）的可行性和安全性。所使用的设备是Optimo Regen（OR），它能够提供以损伤为导向的训练和特定任务训练。
这是一项单中心、随机、单盲、双臂、平行组对照试验。符合标准的患者被随机分为RMIT组或RMIT + RMTT组，并在标准护理的基础上接受20小时的机器人治疗。
共招募了4名患者，每组各有2名患者接受治疗。该研究是可行的，入组率为66.7%，完成率为75%，每次干预课程的出勤率为100%。我们实现了90%的满意率，且无严重不良反应。所有患者在1个月时运动力量、上肢Fugl-Meyer评估（FMA-UE）、功能独立性测量（FIM）、医院焦虑抑郁量表（HADS）和生活质量评分均有改善。干预开始后3个月，FIM继续改善。该设备使用相对简便。
该试验是可行的。有必要进行一项全面研究，以比较RMIT和RMTT，后者是一种新的应用。
