Biglan A W, Gonnering R, Lockhart L B, Rabin B, Fuerste F H
Am J Ophthalmol. 1986 Feb 15;101(2):232-5. doi: 10.1016/0002-9394(86)90601-x.
To test the possibility of the formation of an antibody to botulinum A toxin after multiple injections of this potent neurotoxin, we collected serum samples from 28 patients who received 57 doses. These injections over a nine-month period with as much as 50 units per injection formed no detectable antibody.
