Department of Colorectal Surgery, Dandenong Hospital, Monash Health, Dandenong, Australia.
Department of General Surgery, Alfred Hospital, Melbourne, Australia.
ANZ J Surg. 2024 Nov;94(11):2053-2061. doi: 10.1111/ans.19258. Epub 2024 Oct 28.
Haemorrhoids remain a highly prevalent condition in Australia, affecting 39% of the adult Australian population. While haemorrhoidectomy remains the gold standard in the management of haemorrhoids, newer techniques such as haemorrhoid artery ligation-recto anal repair (HAL-RAR) are emerging as promising management modalities. We compare the efficacy of non-Doppler guided (non-DG) HAL-RAR versus Doppler-guided (DG) HAL-RAR in the management of haemorrhoids.
This study was registered with PROSPERO (CRD42022353806) and adhered to PRISMA 2020 guidelines. We conducted a systematic review using Medline, Embase and Cochrane database for comparative studies between Doppler-guided HAL-RAR and non-Doppler-guided HAL-RAR in accordance with the PRISMA 2020 statement for reporting systematic reviews.
Five studies were included in our systematic review and meta-analysis. There was no clinically significant difference in operative times (SMD 0.46, 9% CI -3.16 0 4.08, P = 0.804) or post-operative bleeding (P = 0.142) between the two groups. DG HAL-RAR patients were more likely to have post-operative urinary retention (P < 0.001). Non-DG patients were less likely to experience recurrence (OR 5.12, P < 0.001).
Our review of non-DG HAL-RAR compared to DG HAL-RAR reflects the non-inferiority of the non-DG HALRAR procedure. We hope that these results would provide a guide to clinicians performing HAL-RAR, and would provide some cost savings for institutions who are unable to procure the necessary equipment for DG HAL-RAR.
痔疮仍然是澳大利亚一种高发疾病,影响了 39%的澳大利亚成年人口。尽管痔切除术仍然是痔疮治疗的金标准,但诸如痔动脉结扎-直肠肛门修复术(HAL-RAR)等新技术正作为有前途的治疗方法而出现。我们比较了非多普勒引导(非 DG)HAL-RAR 与多普勒引导(DG)HAL-RAR 在痔疮治疗中的效果。
本研究在 PROSPERO(CRD42022353806)上进行了注册,并遵循 PRISMA 2020 指南。我们使用 Medline、Embase 和 Cochrane 数据库进行了系统评价,以比较符合 PRISMA 2020 报告系统评价声明的多普勒引导 HAL-RAR 与非多普勒引导 HAL-RAR 之间的比较研究。
我们的系统评价和荟萃分析纳入了 5 项研究。两组之间的手术时间(SMD 0.46,9%CI-3.16 0 4.08,P=0.804)或术后出血(P=0.142)没有临床显著差异。DG HAL-RAR 患者更有可能发生术后尿潴留(P<0.001)。非 DG 患者发生复发的可能性较小(OR 5.12,P<0.001)。
我们对非 DG HAL-RAR 与 DG HAL-RAR 的比较反映了非 DG HALRAR 手术的非劣效性。我们希望这些结果能够为进行 HAL-RAR 的临床医生提供指导,并为那些无法获得 DG HAL-RAR 所需设备的机构节省一些成本。