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胃旁路术后转为十二指肠转位术是否安全?短期结果回顾。

Is conversion to duodenal switch after Roux-en-Y gastric bypass safe? Short-term outcomes review.

作者信息

Law William, Ortega-Goddard Emily, Giorgi Marcoandrea, Luhrs Andrew

机构信息

Department of Surgery, Brown University/The Miriam Hospital, 164 Summit Avenue, Providence, RI, 02906, USA.

出版信息

Surg Endosc. 2024 Dec;38(12):7435-7439. doi: 10.1007/s00464-024-11345-1. Epub 2024 Oct 28.

Abstract

BACKGROUND

Weight regain after Roux-en-Y gastric bypass (RYGB) can be seen in approximately 20% of patients. Surgical management options include revision of RYGB and conversion to duodenal switch (DS). Using recently included revisional surgery variables in the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database, we compared the safety and efficacy of RYGB revision versus conversion to DS.

METHODS

An analysis of the 2020 MBSAQIP Participant Use Data File (PUF) revealed 1421 patients who underwent revision of RYGB (n = 1255) or conversion from RYGB to DS (n = 166) for inadequate weight loss or weight regain. Patient characteristics, preoperative body mass index (BMI), operating room (OR) time, and 30-day complications were compared between groups.

RESULTS

When compared with the revision RYGB group, the DS group had higher mean BMI (47.5 vs 42.7, p < 0.001) and longer operative time (209.1 vs 133.4 min, p < 0.001). DS had higher rates of any complication compared to revision RYGB (22.3 vs 5.58%, p < 0.001). DS had higher 30-day readmission rates (16.3 vs 5.50%, p < 0.001), reoperation within 30 days (9.04 vs 2.87%, p < 0.001), venous thromboembolism (VTE) (3.01 vs 0.08%, p < 0.001), intensive care unit (ICU) admission (8.43 vs 0.72%, p < 0.001), anastomotic leak (7.83 vs 0.40%, p < 0.001), surgical site occurrence (SSO) (11.5 vs 2.71%, p < 0.001), and death (0.60 vs 0%, p < 0.001).

CONCLUSION

This short-term data suggests that conversion of RYGB to DS is associated with higher rates of postoperative complications when compared with revision of RYGB. Given the complexity of the procedure, it is best performed by experienced surgeons with careful consideration given to appropriate patient selection and only after extensive patient counseling on associated risks and complications.

摘要

背景

胃旁路手术(RYGB)后体重反弹在约20%的患者中可见。手术管理选择包括RYGB修正术和转为十二指肠转位术(DS)。利用代谢与减重手术认证及质量改进计划(MBSAQIP)数据库中最近纳入的修正手术变量,我们比较了RYGB修正术与转为DS的安全性和有效性。

方法

对2020年MBSAQIP参与者使用数据文件(PUF)的分析显示,1421例患者因减重不足或体重反弹接受了RYGB修正术(n = 1255)或从RYGB转为DS(n = 166)。比较了两组患者的特征、术前体重指数(BMI)、手术室(OR)时间和30天并发症情况。

结果

与RYGB修正术组相比,DS组的平均BMI更高(47.5对42.7,p < 0.001),手术时间更长(209.1对133.4分钟,p < 0.001)。与RYGB修正术相比,DS的任何并发症发生率更高(22.3%对5.58%,p < 0.001)。DS的30天再入院率更高(16.3%对5.50%,p < 0.001),30天内再次手术率更高(9.04%对2.87%,p < 0.001),静脉血栓栓塞(VTE)发生率更高(3.01%对0.08%,p < 0.001),重症监护病房(ICU)入院率更高(8.43%对0.72%,p < 0.001),吻合口漏发生率更高(7.83%对0.40%,p < 0.001),手术部位感染(SSO)发生率更高(11.5%对2.71%,p < 0.001),死亡率更高(0.60%对0%,p < 0.001)。

结论

这些短期数据表明,与RYGB修正术相比RYGB转为DS术后并发症发生率更高。鉴于该手术的复杂性,最好由经验丰富的外科医生进行,要仔细考虑合适的患者选择,并且仅在对相关风险和并发症对患者进行充分咨询后进行。

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