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一项关于神经反馈联合学习风格剖析干预训练对高功能自闭症儿童影响的前瞻性随机对照研究

[A prospective randomized controlled study of neurofeedback combined with learning style profile intervention training in children with high-functioning autism].

作者信息

Huang Ming-Xin, Yu Qing, Li Yuan-Yuan

机构信息

Department of Psychology, Tianjing Children's Hospital/Children's Hospital, Tianjin University, Tianjing 300134, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2024 Oct 15;26(10):1066-1071. doi: 10.7499/j.issn.1008-8830.2405054.

Abstract

OBJECTIVES

To explore the application of neurofeedback (NFB) combined with learning style profile (LSP) intervention training in children with high-functioning autism (HFA).

METHODS

A prospective study was conducted to select 86 children with HFA admitted to the hospital from February 2022 to February 2024. They were divided into two groups according to the random number table method, with 43 cases in each group. In this double-blind study, the control group was given LSP intervention training, and the observation group was given NFB intervention on the basis of the treatment used in the control group. Both groups were treated for 6 months. The scores of Autism Behavior Checklist (ABC), Autism Treatment Evaluation Checklist (ATEC), Social Responsiveness Scale (SRS), and Pediatric Quality of Life (PedsQL) were compared between the two groups before intervention and at 6 months after intervention. The relationship of PedsQL score with ABC, ATEC, and SRS scores was analyzed in children with HFA.

RESULTS

After 6 months of intervention, the scores of ABC, ATEC, and SRS in the observation group were significantly lower than those in the control group, while the PedsQL score in the observation group was significantly higher than that in the control group (<0.05). The PedsQL score was negatively correlated with the ABC, ATEC, and SRS scores in children with HFA (=-0.238, -0.381, -0.219 respectively; <0.001).

CONCLUSIONS

NFB combined with LSP can effectively improve the clinical symptoms and social ability, control the development of the disease, and improve the quality of life in children with HFA.

摘要

目的

探讨神经反馈(NFB)联合学习风格剖析(LSP)干预训练在高功能自闭症(HFA)儿童中的应用。

方法

进行一项前瞻性研究,选取2022年2月至2024年2月入院的86例HFA儿童。根据随机数字表法将他们分为两组,每组43例。在这项双盲研究中,对照组给予LSP干预训练,观察组在对照组治疗基础上给予NFB干预。两组均治疗6个月。比较两组干预前及干预6个月后的自闭症行为量表(ABC)、自闭症治疗评估量表(ATEC)、社会反应量表(SRS)和儿童生活质量量表(PedsQL)得分。分析HFA儿童中PedsQL得分与ABC、ATEC和SRS得分的关系。

结果

干预6个月后,观察组的ABC、ATEC和SRS得分显著低于对照组,而观察组的PedsQL得分显著高于对照组(<0.05)。HFA儿童中PedsQL得分与ABC、ATEC和SRS得分呈负相关(分别为=-0.238、-0.381、-0.219;<0.001)。

结论

NFB联合LSP可有效改善HFA儿童的临床症状和社交能力,控制疾病发展,提高生活质量。

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