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使用眼前节光学相干断层扫描测量泪膜半月板高度对白内障术前泪道阻塞的诊断价值。

Diagnostic utility of tear meniscus height measurement using anterior segment optical coherence tomography for lacrimal passage disorder before cataract surgery.

机构信息

Department of Ophthalmology, Japanese Red Cross Society Osaka Hospital, Osaka, Japan.

出版信息

Sci Rep. 2024 Oct 28;14(1):25866. doi: 10.1038/s41598-024-75979-w.

Abstract

To evaluate diagnostic utility of tear meniscus height (TMH) measurement using anterior segment optical coherence tomography (AS-OCT) for lacrimal passage disorder (LPD) in patients scheduled for cataract surgery. Patients with cataracts were enrolled. Lacrimal irrigation test was used to diagnose LPD. TMH measurement was performed using prior to cataract surgery. A receiver operating characteristic curve analysis was performed to calculate the cutoff value of TMH to detect LPD. Correlation between TMH and age, sex, LPD, use of glaucoma eyedrops, and use of dry eye drops in patients with and without LPD was evaluated. Sixty-six patients (127 eyes) were included, of which 12 (9.4%) eyes had LPD. The mean TMH was significantly higher in the LPD group than in the non-LPD group (P = 0.007). Multiple regression analysis revealed a significant association of TMH with LPD (P = 0.000). With an area under the curve of 0.740, the optimal cut-off TMH value was 401.0 μm. The sensitivity and specificity of this cutoff value were 58.3% and 83.0%, respectively. These findings demonstrate the diagnostic utility of TMH, measured using AS-OCT, for LPD. This suggests that AS-OCT is useful for preoperative exclusion of LPD.

摘要

评估使用眼前段光学相干断层扫描(AS-OCT)测量泪膜半月板高度(TMH)对计划行白内障手术的患者的泪道阻塞(LPD)的诊断效用。纳入白内障患者。使用泪道冲洗试验来诊断 LPD。在白内障手术前进行 TMH 测量。使用受试者工作特征曲线分析来计算 TMH 的截断值以检测 LPD。评估有和无 LPD 的患者中 TMH 与年龄、性别、LPD、青光眼眼药水使用和干眼症眼药水使用之间的相关性。共纳入 66 名患者(127 只眼),其中 12 只眼(9.4%)患有 LPD。LPD 组的 TMH 平均值明显高于非 LPD 组(P=0.007)。多元回归分析显示 TMH 与 LPD 显著相关(P=0.000)。曲线下面积为 0.740,最佳截断 TMH 值为 401.0 μm。该截断值的敏感性和特异性分别为 58.3%和 83.0%。这些发现表明 AS-OCT 测量的 TMH 对 LPD 具有诊断效用。这表明 AS-OCT 可用于术前排除 LPD。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a17c/11519514/5a8b1bddd7d6/41598_2024_75979_Fig1_HTML.jpg

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