Departments of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
Int Ophthalmol. 2023 Apr;43(4):1135-1141. doi: 10.1007/s10792-022-02511-2. Epub 2022 Sep 13.
To analyze the relationship between tear meniscus dimensions and higher-order aberrations (HOAs) in patients with lacrimal passage obstruction using anterior segment optical coherence tomography (AS-OCT).
This study was a retrospective observational study of 71 eyes of 49 patients with lacrimal passage obstruction. These patients received sheath-guided dacryoendoscopic probing and bicanalicular intubation (SG-BCI) at Toyama University Hospital between August 2020 and October 2021. Using AS-OCT, tear meniscus height (TMH), tear meniscus area (TMA), and total corneal HOAs values were measured before and after surgery.
Surgical success was achieved in 69 eyes (97.1%). At the final observation, 62 eyes showed lacrimal patency (89.8%). The preoperative TMH, TMA, and HOAs values were 1.55 ± 0.96 mm, 0.11 ± 0.14 mm, and 0.37 ± 0.27 µm, respectively, and the final postoperative TMH, TMA, and HOAs values were 0.97 ± 0.74 mm (p < 0.0001), 0.06 ± 0.11 mm (p = 0.02), and 0.29 ± 0.16 µm (p = 0.001), respectively. The results showed a significant improvement. The changes in HOAs before and after surgery were positively correlated with the changes in TMH (r = 0.3476, p = 0.0241) and TMA (r = 0.3653, p = 0.0174).
SG-BCI for lacrimal passage obstruction resulted in a significant decrease in measured HOAs. The decrease in HOAs was correlated with decreases in tear meniscus dimensions.
使用眼前节光学相干断层扫描（AS-OCT）分析泪道阻塞患者的泪膜半月板尺寸与高阶像差（HOAs）之间的关系。
本研究为前瞻性观察研究，纳入 2020 年 8 月至 2021 年 10 月在富山大学医院接受鞘管引导泪道内镜探查和双泪小管插管（SG-BCI）治疗的 49 例（71 眼）泪道阻塞患者。使用 AS-OCT 分别于术前和术后测量泪膜半月板高度（TMH）、泪膜半月板面积（TMA）和总角膜 HOAs 值。
69 眼（97.1%）手术成功。末次观察时，62 眼（89.8%）泪道通畅。术前 TMH、TMA 和 HOAs 值分别为 1.55±0.96mm、0.11±0.14mm 和 0.37±0.27μm，术后最终 TMH、TMA 和 HOAs 值分别为 0.97±0.74mm（p＜0.0001）、0.06±0.11mm（p=0.02）和 0.29±0.16μm（p=0.001），均较术前显著改善。术后 HOAs 的变化与 TMH（r=0.3476，p=0.0241）和 TMA（r=0.3653，p=0.0174）的变化呈正相关。
SG-BCI 治疗泪道阻塞可显著降低测量的 HOAs。HOAs 的降低与泪膜半月板尺寸的降低相关。
