Schumacher Andrea M, Tschitsaz Armita, Lerch Stefan, Wyssen Andrea, Schlensog-Schuster Franziska, Mürner-Lavanchy Ines, Koenig Julian, Cavelti Marialuisa, Kaess Michael
University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Division of Youth Mental Health, Faculty of Psychology, University of Basel, Basel, Switzerland.
Eur Eat Disord Rev. 2025 Mar;33(2):360-373. doi: 10.1002/erv.3146. Epub 2024 Oct 28.
Impairments in personality functioning (PF) according to the Alternative Model of Personality Disorders (AMPD) may affect anorexia nervosa (AN) and its treatment. However, PF impairments in adolescents with AN have not been studied. This case-control study analysed PF impairments in adolescent inpatients suffering from AN compared to a clinical control group (CC) and investigated the relationship of PF with AN severity.
Adolescent patients with AN (n = 43) and CC (n = 127) were matched by age, sex, and global functioning. Validated interviews were applied to assess impairments in PF (Semi-Structured Interview for Personality Functioning, STiP-5.1) and severity of AN (Eating Disorder Examination, EDE), as well as weight measures. Group comparisons of PF impairment and the relationship between PF impairment and AN severity were analysed using multiple linear regression.
AN patients showed greater impairment in the facet 'self-esteem' (p = 0.033, Cohen's f = 0.036) than CC. In AN patients, impairments in the domain 'self-functioning' (p = 0.003, Cohen's f = 0.254) and its underlying element 'identity' (p = 0.016, Cohen's f = 0.172) were associated with AN severity (EDE). Additionally, higher impairments in two facets of 'empathy' (p = 0.019, Cohen's f = 0.223) and 'intimacy' (p = 0.026, Cohen's f = 0.199) were associated with higher AN severity (lower BMI percentiles).
These results support theoretical frameworks of AN and highlight the importance of PF impairments in understanding and treating AN. Future research should investigate how impairments in PF affect AN development and treatment response through longitudinal studies.
根据人格障碍替代模型(AMPD),人格功能(PF)受损可能会影响神经性厌食症(AN)及其治疗。然而,青少年神经性厌食症患者的人格功能受损情况尚未得到研究。本病例对照研究分析了与临床对照组(CC)相比,青少年神经性厌食症住院患者的人格功能受损情况,并研究了人格功能与神经性厌食症严重程度之间的关系。
将青少年神经性厌食症患者(n = 43)和临床对照组(n = 127)按年龄、性别和整体功能进行匹配。采用经过验证的访谈来评估人格功能受损情况(人格功能半结构化访谈,STiP-5.1)、神经性厌食症的严重程度(饮食失调检查,EDE)以及体重指标。使用多元线性回归分析人格功能受损的组间比较以及人格功能受损与神经性厌食症严重程度之间的关系。
与临床对照组相比,神经性厌食症患者在“自尊”方面的受损程度更大(p = 0.033,科恩f = 0.036)。在神经性厌食症患者中,“自我功能”领域(p = 0.003,科恩f = 0.254)及其潜在要素“身份认同”(p = 0.016,科恩f = 0.172)的受损与神经性厌食症严重程度(EDE)相关。此外,“共情”(p = 0.019,科恩f = 0.223)和“亲密关系”(p = 0.026,科恩f = 0.199)两个方面的更高受损与更高的神经性厌食症严重程度(更低的体重指数百分位数)相关。
这些结果支持了神经性厌食症的理论框架,并突出了人格功能受损在理解和治疗神经性厌食症中的重要性。未来的研究应通过纵向研究调查人格功能受损如何影响神经性厌食症的发展和治疗反应。