Tezen Ozan, Hayıroğlu Mert İlker, Pay Levent, Yumurtaş Ahmet Çağdaş, Keskin Kıvanç, Çetin Tuğba, Dereli Şeyda, Kadığoğlu Hikmet, Yücedağ Furkan Fatih, Arter Ertan, Dayı Şennur Ünal
Department of Cardiology, Bayrampasa State Hospital, Istanbul, Turkey.
Department of Cardiology, Dr Siyami Ersek Thoracic & Cardiovascular Surgery Training Hospital, Istanbul, Turkey.
Biomark Med. 2024;18(21-22):937-944. doi: 10.1080/17520363.2024.2415284. Epub 2024 Oct 29.
Systemic immune-inflammation index (SII) is obtained by multiplying the platelets by the ratio of neutrophils to lymphocytes. We aimed to examine the relationship between contrast induced nephropathy (CIN) development and SII in non-ST-segment elevation myocardial infarction (NSTEMI) patients. 1124 NSTEMI patients included and divided into two groups according to the development of CIN. The relationship between SII and CIN development was examined. Among two groups, significant differences were observed in terms of age, chronic renal failure, presence of critical stenoses in the LAD, SII and C-reactive protein (CRP). It was calculated that a value of 709 and above for SII had a predictive power with 74% sensitivity and 74% specificity for CIN. SII has the potential to predict the development of CIN in NSTEMI patients.
全身免疫炎症指数(SII)通过血小板乘以中性粒细胞与淋巴细胞的比值得出。我们旨在研究非ST段抬高型心肌梗死(NSTEMI)患者中对比剂诱导的肾病(CIN)发生与SII之间的关系。纳入1124例NSTEMI患者,并根据CIN的发生情况分为两组。研究了SII与CIN发生之间的关系。两组在年龄、慢性肾功能衰竭、左前降支严重狭窄、SII和C反应蛋白(CRP)方面存在显著差异。计算得出SII值709及以上对CIN具有预测能力,敏感性为74%,特异性为74%。SII有可能预测NSTEMI患者CIN的发生。