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Does T-tube indwelling prolong the procedure of endoscopic retrograde cholangiopancreatography for healing duct-to-duct anastomotic bile leakage after liver transplantation?T 型管留置是否会延长肝移植后胆管吻合口胆漏内镜逆行胰胆管造影的治疗时间?
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LIVER TRANSPLANTATION: TACROLIMUS BLOOD LEVELS VARIATION AND SURVIVAL, REJECTION AND DEATH OUTCOMES.肝移植:他克莫司血药浓度变化与生存、排斥反应和死亡结局。
Arq Gastroenterol. 2021 Jul-Sep;58(3):370-376. doi: 10.1590/S0004-2803.202100000-62.
2
Endoscopic management of bile leaks after liver transplantation: An analysis of two high-volume transplant centers.肝移植术后胆漏的内镜治疗:两个高容量移植中心的分析
United European Gastroenterol J. 2018 Feb;6(1):89-96. doi: 10.1177/2050640617712869. Epub 2017 May 25.
3
An Update on Endoscopic Management of Post-Liver Transplant Biliary Complications.肝移植术后胆道并发症的内镜治疗进展
Clin Endosc. 2017 Sep;50(5):451-463. doi: 10.5946/ce.2016.139. Epub 2017 Apr 17.
4
Endoscopic management of biliary complications after liver transplantation: An evidence-based review.肝移植术后胆道并发症的内镜治疗:一项循证综述
World J Gastrointest Endosc. 2015 Jun 10;7(6):606-16. doi: 10.4253/wjge.v7.i6.606.
5
Endoscopic management of bile leakage after liver transplantation.肝移植术后胆漏的内镜治疗
Gut Liver. 2015 May 23;9(3):417-23. doi: 10.5009/gnl14117.
6
Endoscopic treatment of nonstricture-related benign biliary diseases using covered self-expandable metal stents.使用覆膜自膨式金属支架内镜治疗非狭窄相关良性胆道疾病
Endoscopy. 2015 Apr;47(4):315-21. doi: 10.1055/s-0034-1391093. Epub 2014 Dec 18.
7
Biliary complications after orthotopic liver transplantation.原位肝移植术后的胆道并发症。
Curr Opin Organ Transplant. 2014 Jun;19(3):209-16. doi: 10.1097/MOT.0000000000000082.
8
Biliary complications following liver transplantation.肝移植术后胆道并发症。
World J Gastroenterol. 2013 May 21;19(19):2841-6. doi: 10.3748/wjg.v19.i19.2841.
9
Post-transplant biliary complications: an analysis from a predominantly living donor liver transplant center.移植后胆道并发症:主要来自活体供肝移植中心的分析。
J Gastroenterol Hepatol. 2013 Jun;28(6):1056-60. doi: 10.1111/jgh.12169.
10
Biliary complications after liver transplantation: old problems and new challenges.肝移植术后胆道并发症:老问题与新挑战。
Am J Transplant. 2013 Feb;13(2):253-65. doi: 10.1111/ajt.12034. Epub 2013 Jan 17.

T 型管留置是否会延长肝移植后胆管吻合口胆漏内镜逆行胰胆管造影的治疗时间?

Does T-tube indwelling prolong the procedure of endoscopic retrograde cholangiopancreatography for healing duct-to-duct anastomotic bile leakage after liver transplantation?

机构信息

Division of Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University, Shulan International Medical College, Hangzhou, Zhejiang, P.R. China.

出版信息

Medicine (Baltimore). 2024 Oct 25;103(43):e40191. doi: 10.1097/MD.0000000000040191.

DOI:10.1097/MD.0000000000040191
PMID:39470552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11521000/
Abstract

Endoscopic retrograde cholangiopancreatography (ERCP) is the preferred treatment for duct-to-duct anastomotic bile leakage (D-D aBL) after liver transplantation (LT). This study aimed to compare the time required for ERCP and D-D aBL recovery in post-LT patients with and without T-tube drainage. A total of 40 patients (11 with T-tube drainage and 29 without T-tube drainage) with confirmed D-D aBLs treated successfully with ERCP from July 2016 to September 2021 were reviewed. The mean interval from LT to initial ERCP was significantly longer in patients with T-tube drainage than in those without T-tube drainage (41.9 vs 25.1 days, P < .05). However, there was no significant difference in the time required for ERCP to result in D-D aBL healing between patients with T-tube drainage and those without T-tubes (33.4 vs 23.0 days). T-tube indwelling did not significantly prolong the course required for ERCP to resolve D-D aBL in post-LT patients.

摘要

经内镜逆行胰胆管造影术(ERCP)是肝移植(LT)后胆管对胆管吻合口胆漏(D-D aBL)的首选治疗方法。本研究旨在比较 LT 后有和无 T 管引流的患者行 ERCP 治疗和 D-D aBL 恢复所需的时间。回顾性分析 2016 年 7 月至 2021 年 9 月期间 40 例经 ERCP 成功治疗的确诊 D-D aBL 患者(11 例有 T 管引流,29 例无 T 管引流)。有 T 管引流的患者从 LT 到首次 ERCP 的平均间隔时间明显长于无 T 管引流的患者(41.9 天 vs 25.1 天,P<0.05)。然而,有 T 管引流和无 T 管引流的患者行 ERCP 治愈 D-D aBL 所需的时间无显著差异(33.4 天 vs 23.0 天)。T 管留置并没有显著延长 LT 后患者行 ERCP 治疗 D-D aBL 所需的时间。