Center of Clinical Investigations, INSERM CIC1426, Robert Debré University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP) Nord, Paris, France.
URP7323 Perinatal and Pediatric Pharmacology and Therapeutic Assessment, Paris Cité University, Paris, France.
JAMA Netw Open. 2024 Oct 1;7(10):e2441874. doi: 10.1001/jamanetworkopen.2024.41874.
Mental disorders among the pediatric population are a major area of public health concern. Little is known regarding changes in pediatric hospital resource use related to mental health (MH) long after the onset of the COVID-19 pandemic in March 2020.
To assess rates and trends of hospitalizations and emergency department (ED) visits related to MH and self-harm (SH) among children before and during the 3 years following the pandemic onset.
DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used national hospital data. The study sample included all MH- and SH-related hospitalizations and ED visits among children aged 6 to 17 years in France between January 1, 2016, to May 31, 2023.
Interrupted time-series analysis of monthly rates of MH- and SH-related hospitalizations and ED visits per 100 000 children was conducted to assess changes before and every year after the pandemic onset. Rate ratios (RRs) between estimated and expected rates were calculated.
Overall, 583 244 hospitalizations (81.4% for MH and 18.6% for SH) and 432 725 ED visits (79.9% for MH and 20.1% for SH) were analyzed. The mean (SD) age of the children was 13.7 (2.9) and 14.8 (1.7) years for MH-related and SH-related hospitalizations, respectively, and 14.2 (2.6) and 14.6 (2.1) years for MH-related and SH-related ED visits, respectively. For MH-related hospitalizations, 52.6% were female and 47.4% were male; for SH-related hospitalizations, 83.1% were female and 16.9% were male. For MH-related ED visits, 62.8% were female and 37.2% were male; for SH-related ED visits, 77.4% were female and 22.6% were male. Before the pandemic, an increasing trend in all monthly rates, except that of MH-related hospitalizations, was observed. After an immediate decrease in hospitalization and ED visit rates during the initial pandemic period (March 1 to May 31, 2020), trends increased in the first 2 years following the pandemic onset and decreased thereafter. Overall, rates of MH-related hospitalizations and ED visits exceeded expected rates in only the second year after the pandemic onset, with increases of 6.0% (RR, 1.06 [95% CI, 1.05-1.06]) and 5.0% (RR, 1.05 [95% CI, 1.04-1.05]), respectively. However, rates of hospitalizations and ED visits for behavioral syndromes (mainly eating and sleeping disorders) persistently exceeded expected rates, with increases of 29.0% (RR, 1.29 [95% CI, 1.25-1.34]) and 26.0% (RR, 1.26 [95% CI, 1.21-1.31]) in the third year, respectively. Likewise, rates of SH-related hospitalizations and ED visits persistently rose above expected rates, with increases of 29.0% (RR, 1.29 [95% CI, 1.26-1.32]) and 43.0% (RR, 1.43 [95% CI, 1.40-1.47]) in the third year, respectively.
In this cross-sectional study, persistent increases in the use of hospital resources to treat eating and sleeping disorders and intentional SH among pediatric patients were observed long after the onset of the COVID-19 pandemic. These findings warrant future research to identify persistent stress factors in children.
儿科人群中的精神障碍是公共卫生的一个主要关注领域。在 2020 年 3 月 COVID-19 大流行开始后的很长一段时间里,人们对与心理健康 (MH) 相关的儿科医院资源使用的变化知之甚少。
评估大流行开始前后 3 年内与儿童 MH 和自伤 (SH) 相关的住院和急诊 (ED) 就诊的发生率和趋势。
设计、地点和参与者:这是一项横断面研究,使用了国家医院数据。研究样本包括 2016 年 1 月 1 日至 2023 年 5 月 31 日期间法国 6 至 17 岁儿童 MH 和 SH 相关住院和 ED 就诊的所有病例。
采用每月 MH 和 SH 相关住院和 ED 就诊率的中断时间序列分析,评估大流行前和大流行后每年的变化。计算估计和预期比率之间的比率比 (RR)。
共分析了 583244 例住院治疗(81.4%为 MH,18.6%为 SH)和 432725 例 ED 就诊(79.9%为 MH,20.1%为 SH)。儿童的平均(SD)年龄分别为 MH 相关住院和 SH 相关住院 13.7(2.9)岁和 14.8(1.7)岁,MH 相关 ED 就诊和 SH 相关 ED 就诊分别为 14.2(2.6)岁和 14.6(2.1)岁。MH 相关住院治疗中,女性占 52.6%,男性占 47.4%;SH 相关住院治疗中,女性占 83.1%,男性占 16.9%。MH 相关 ED 就诊中,女性占 62.8%,男性占 37.2%;SH 相关 ED 就诊中,女性占 77.4%,男性占 22.6%。大流行前,除 MH 相关住院治疗外,所有月度率均呈上升趋势。在 COVID-19 大流行初期(2020 年 3 月 1 日至 5 月 31 日)住院和 ED 就诊率立即下降后,大流行后前 2 年呈上升趋势,此后下降。总体而言,只有在大流行后第二年,MH 相关住院和 ED 就诊率才超过预期水平,分别增加了 6.0%(RR,1.06[95%CI,1.05-1.06])和 5.0%(RR,1.05[95%CI,1.04-1.05])。然而,行为综合征(主要是饮食和睡眠障碍)的住院和 ED 就诊率持续超过预期水平,第三年分别增加了 29.0%(RR,1.29[95%CI,1.25-1.34])和 26.0%(RR,1.26[95%CI,1.21-1.31])。同样,SH 相关住院和 ED 就诊率也持续上升,第三年分别增加了 29.0%(RR,1.29[95%CI,1.26-1.32])和 43.0%(RR,1.43[95%CI,1.40-1.47])。
在这项横断面研究中,在 COVID-19 大流行开始后的很长一段时间内,治疗儿童饮食和睡眠障碍以及故意自伤的医院资源使用持续增加。这些发现需要进一步研究,以确定儿童持续存在的压力因素。