Kumar S Santhosh, S P Sasirekha, R Santhosh
Department of Computer Science and Engineering, Faculty of Engineering, Karpagam Academy of Higher Education, Coimbatore, India.
Electromagn Biol Med. 2024 Oct;43(4):267-291. doi: 10.1080/15368378.2024.2390058. Epub 2024 Oct 29.
Brain tumors present a formidable diagnostic challenge due to their aberrant cell growth. Accurate determination of tumor location and size is paramount for effective diagnosis. Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) are pivotal tools in clinical diagnosis, yet tumor segmentation within their images remains challenging, particularly at boundary pixels, owing to limited sensitivity. Recent endeavors have introduced fusion-based strategies to refine segmentation accuracy, yet these methods often prove inadequate. In response, we introduce the Parallel-Way framework to surmount these obstacles. Our approach integrates MRI and PET data for a holistic analysis. Initially, we enhance image quality by employing noise reduction, bias field correction, and adaptive thresholding, leveraging Improved Kalman Filter (IKF), Expectation Maximization (EM), and Improved Vibe Algorithm (IVib), respectively. Subsequently, we conduct multi-modality image fusion through the Dual-Tree Complex Wavelet Transform (DTWCT) to amalgamate data from both modalities. Following fusion, we extract pertinent features using the Advanced Capsule Network (ACN) and reduce feature dimensionality via Multi-objective Diverse Evolution-based selection. Tumor segmentation is then executed utilizing the Twin Vision Transformer with dual attention mechanism. Implemented our Parallel-Way framework which exhibits heightened model performance. Evaluation across multiple metrics, including accuracy, sensitivity, specificity, F1-Score, and AUC, underscores its superiority over existing methodologies.
脑肿瘤因其异常的细胞生长而带来了巨大的诊断挑战。准确确定肿瘤的位置和大小对于有效诊断至关重要。磁共振成像(MRI)和正电子发射断层扫描(PET)是临床诊断中的关键工具,然而,由于灵敏度有限,在其图像内进行肿瘤分割仍然具有挑战性,尤其是在边界像素处。最近的努力引入了基于融合的策略来提高分割精度,但这些方法往往被证明是不够的。作为回应,我们引入了并行路径框架来克服这些障碍。我们的方法整合了MRI和PET数据进行全面分析。首先,我们分别利用改进的卡尔曼滤波器(IKF)、期望最大化(EM)和改进的Vibe算法(IVib),通过降噪、偏置场校正和自适应阈值处理来提高图像质量。随后,我们通过双树复数小波变换(DTWCT)进行多模态图像融合,以合并来自两种模态的数据。融合后,我们使用高级胶囊网络(ACN)提取相关特征,并通过基于多目标多样进化的选择来降低特征维度。然后利用具有双注意力机制的孪生视觉Transformer进行肿瘤分割。实现了我们的并行路径框架,其表现出更高的模型性能。在包括准确率、灵敏度、特异性、F1分数和AUC在内的多个指标上的评估强调了其相对于现有方法的优越性。