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本文引用的文献

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Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy.糖尿病感觉运动性周围神经病变的发病机制、诊断和临床管理。
Nat Rev Endocrinol. 2021 Jul;17(7):400-420. doi: 10.1038/s41574-021-00496-z. Epub 2021 May 28.
2
Prevalence of peripheral neuropathy in pre-diabetes: a systematic review.糖尿病前期周围神经病变的患病率:系统评价。
BMJ Open Diabetes Res Care. 2021 May;9(1). doi: 10.1136/bmjdrc-2020-002040.
3
Peripheral Neuropathy and All-Cause and Cardiovascular Mortality in U.S. Adults : A Prospective Cohort Study.美国成年人外周神经病变与全因和心血管死亡率:一项前瞻性队列研究。
Ann Intern Med. 2021 Feb;174(2):167-174. doi: 10.7326/M20-1340. Epub 2020 Dec 8.
4
Diagnosing peripheral neuropathy in South-East Asia: A focus on diabetic neuropathy.诊断东南亚的周围神经病变:关注糖尿病性周围神经病变。
J Diabetes Investig. 2020 Sep;11(5):1097-1103. doi: 10.1111/jdi.13269. Epub 2020 May 21.
5
New Perspective in Diabetic Neuropathy: From the Periphery to the Brain, a Call for Early Detection, and Precision Medicine.糖尿病神经病变的新视角:从外周到大脑,呼吁早期检测与精准医学。
Front Endocrinol (Lausanne). 2020 Jan 17;10:929. doi: 10.3389/fendo.2019.00929. eCollection 2019.
6
Prevalence of peripheral neuropathy in patients with diabetes: A systematic review and meta-analysis.糖尿病患者周围神经病变的患病率:系统评价和荟萃分析。
Prim Care Diabetes. 2020 Oct;14(5):435-444. doi: 10.1016/j.pcd.2019.12.005. Epub 2020 Jan 6.
7
Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program).2 型糖尿病患者的血管并发症:38 个国家的患病率和相关因素(DISCOVER 研究项目)。
Cardiovasc Diabetol. 2018 Nov 28;17(1):150. doi: 10.1186/s12933-018-0787-8.
8
Peripheral Neuropathy: A Practical Approach to Diagnosis and Symptom Management.《周围神经病变:诊断与症状管理实用方法》
Mayo Clin Proc. 2015 Jul;90(7):940-51. doi: 10.1016/j.mayocp.2015.05.004.
9
A systematic review on the nerve-muscle electrophysiology in human organophosphorus pesticide exposure.人类有机磷农药暴露的神经-肌肉电生理学的系统评价。
Hum Exp Toxicol. 2014 Jan;33(1):92-102. doi: 10.1177/0960327113489047. Epub 2013 May 23.
10
Explorative study on diabetes neuropathy among type II diabetic patients in Universiti Sains Malaysia Hospital.马来西亚理科大学医院II型糖尿病患者糖尿病神经病变的探索性研究
Diabetes Metab Syndr. 2012 Jul-Sep;6(3):167-72. doi: 10.1016/j.dsx.2012.09.002. Epub 2012 Oct 26.

马来西亚零售药店中周围神经病变的患病率及相关因素:一项横断面研究。

Prevalence and factors associated with peripheral neuropathy in a setting of retail pharmacies in Malaysia-A cross-sectional study.

机构信息

Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.

Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia.

出版信息

PLoS One. 2024 Oct 29;19(10):e0307093. doi: 10.1371/journal.pone.0307093. eCollection 2024.

DOI:10.1371/journal.pone.0307093
PMID:39471189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11521241/
Abstract

Peripheral neuropathy is a common cause for neurological consultation, especially among those with diabetes mellitus. However, research on peripheral neuropathy among the general population is lacking in Malaysia. This study aimed to determine the prevalence and factors associated with peripheral neuropathy in a setting of retail pharmacies. This cross-sectional study of 1283 participants was conducted at retail pharmacies in Selangor. Peripheral neuropathy was defined as the final score in the mild to severe category in the severity rating scale using a biothesiometer. SPSS version 26 was used to perform the analysis. Multiple logistic regressions were used to determine the factors associated with peripheral neuropathy. The prevalence of peripheral neuropathy based on the biothesiometer was 26.5%. According to multiple logistic regression, the predictors of peripheral neuropathy were those who have diabetes (AOR = 3.901), aged more than 50 years (AOR = 3.376), have secondary education or below (AOR = 2.330), are male (AOR = 1.816), and have underlying hypertension (AOR = 1.662). Peripheral neuropathy is a reasonably prevalent condition, affecting a quarter of the general population, and often goes undiagnosed. It is crucial for healthcare providers to proactively screen for peripheral neuropathy, particularly in high-risk populations, to prevent potential complications.

摘要

周围神经病变是神经科咨询的常见原因,尤其是在糖尿病患者中。然而,马来西亚缺乏针对普通人群周围神经病变的研究。本研究旨在确定在零售药店环境中周围神经病变的患病率和相关因素。这项横断面研究共纳入了 1283 名参与者,在雪兰莪州的零售药店进行。周围神经病变定义为使用生物感觉计的严重程度评分量表中轻度至重度类别中的最终得分。使用 SPSS 版本 26 进行分析。使用多因素逻辑回归确定与周围神经病变相关的因素。根据生物感觉计,周围神经病变的患病率为 26.5%。根据多因素逻辑回归,周围神经病变的预测因素是患有糖尿病(AOR=3.901)、年龄大于 50 岁(AOR=3.376)、接受过中等或以下教育(AOR=2.330)、男性(AOR=1.816)和患有潜在高血压(AOR=1.662)。周围神经病变是一种相当普遍的疾病,影响四分之一的普通人群,而且常常未被诊断出来。医疗保健提供者积极筛查周围神经病变至关重要,特别是在高危人群中,以预防潜在的并发症。