Department of Medical Nursing, School of Nursing, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Sci Rep. 2024 Aug 24;14(1):19662. doi: 10.1038/s41598-024-70314-9.
Diabetic peripheral neuropathy is one of the diabetes most common microvascular complications. It is very prevalent in Sub-Saharan Africa due to a combination of causes, including rising diabetes prevalence, limited healthcare resources, and a lack of access to competent medical care. However, just a few studies have been undertaken in the study area. Institution-based cross-sectional study was conducted in the Amhara region referral hospitals, in 2022. By using a systematic random sampling technique, a total of 627 respondents were included. The data was entered into EPI Data version 4.6 and exported to SPSS version 25 for further analysis. A binary logistic regression was used to determine the relationship between the dependent and predictor variables. The association between predictor variables and the dependent variable was determined using multivariate logistic regression [p value < 0.05, 95% confidence interval]. The overall prevalence of diabetic peripheral neuropathy among the study participants was 48.2% (95% CI; 44.2, 52.1). Aged between 40 and 60 years (AOR = 4:27; 95% CI 2.62, 6.94), and 60 years and older (AOR = 4:47; 95% CI 2.40, 8.35), participants who have lived alone (AOR = 2:14; 95% CI 1.21, 3.79), patients with comorbidity (AOR = 1:83; 95% CI 1.22, 2.76), and being physically inactive (AOR = 1:69; 95% CI 1.14, 2.49) were significantly associated with Diabetic peripheral neuropathy. Diabetic peripheral neuropathy was high among diabetic patients. Healthcare providers should prioritize regular screening and early intervention for individuals at higher risk, particularly those aged 40 and above, those living alone, patients with comorbid conditions, and those who are physically inactive. Implementing community-based support programs, encouraging physical activity, and providing comprehensive management plans for diabetes and associated comorbidities can help mitigate the risk and improve the quality of life for these patients.
糖尿病周围神经病变是糖尿病最常见的微血管并发症之一。由于多种原因，包括糖尿病患病率上升、医疗保健资源有限以及获得合格医疗服务的机会有限，它在撒哈拉以南非洲非常普遍。然而，在研究区域进行的研究很少。2022 年，在阿姆哈拉地区的转诊医院进行了基于机构的横断面研究。通过使用系统随机抽样技术，共纳入了 627 名受访者。数据输入 EPI Data 版本 4.6 并导出到 SPSS 版本 25 进行进一步分析。使用二元逻辑回归来确定因变量和预测变量之间的关系。使用多元逻辑回归确定预测变量与因变量之间的关联[p 值<0.05，95%置信区间]。研究参与者中糖尿病周围神经病变的总患病率为 48.2%（95%CI；44.2，52.1）。年龄在 40 至 60 岁之间的参与者（AOR=4:27；95%CI 2.62,6.94）和 60 岁及以上的参与者（AOR=4:47；95%CI 2.40,8.35）、独居的参与者（AOR=2:14；95%CI 1.21,3.79）、患有合并症的患者（AOR=1:83；95%CI 1.22,2.76）和身体不活跃的患者（AOR=1:69；95%CI 1.14,2.49）与糖尿病周围神经病变显著相关。糖尿病患者中糖尿病周围神经病变的发病率较高。医疗保健提供者应优先为高风险人群（特别是 40 岁及以上人群、独居人群、患有合并症的人群以及身体不活跃的人群）定期进行筛查和早期干预。实施基于社区的支持计划、鼓励身体活动以及为糖尿病和相关合并症提供全面管理计划，有助于降低这些患者的风险并提高生活质量。
