Michael Sars Centre, University of Bergen, Bergen 5008, Norway.
Department of Natural History, University Museum of Bergen, University of Bergen, Bergen 5007, Norway.
Proc Natl Acad Sci U S A. 2024 Nov 5;121(45):e2411499121. doi: 10.1073/pnas.2411499121. Epub 2024 Oct 29.
Reverse development, or the ability to rejuvenate by morphological reorganization into the preceding life cycle stage is thought to be restricted to a few species within Cnidaria. To date, is the only known species capable of undergoing reverse development after the onset of sexual reproduction. Here, we demonstrate that the ctenophore is capable of reversal from mature lobate to early cydippid when fed following a period of stress. Our findings illuminate central aspects of ctenophore development, ecology, and evolution and show the high potential of as a unique model system to study reverse development and rejuvenation. Besides shedding light on the plasticity of developmental programs, these results raise fundamental questions about early animal development, body plans, and life cycles.
逆行发育，或者通过形态重组恢复到先前生命周期阶段的能力，被认为是刺胞动物中少数几种物种所具有的特征。迄今为止，只有 一种已知的物种能够在有性繁殖开始后进行逆行发育。在这里，我们证明了当经过一段时间的压力后喂食时，栉水母 能够从成熟的叶状逆转为早期的浮浪幼虫期。我们的发现阐明了栉水母发育、生态学和进化的核心方面，并展示了 作为一个独特的模型系统来研究逆行发育和返老还童的巨大潜力。除了阐明发育程序的可塑性外，这些结果还提出了关于早期动物发育、体型和生命周期的基本问题。
