糖尿病患者手部关节活动受限（LJM）：与慢性并发症的关系
Limited joint mobility (LJM) of the hand in patients with diabetes mellitus: relation to chronic complications.
作者信息
Starkman H S, Gleason R E, Rand L I, Miller D E, Soeldner J S
出版信息
Ann Rheum Dis. 1986 Feb;45(2):130-5. doi: 10.1136/ard.45.2.130.
Limited joint mobility (LJM) of the hand was studied by visual examination in 361 diabetic outpatients aged 11 to 83 years, and 45 non-diabetic controls, without evidence of arthritis. LJM was evident in 58% of diabetic subjects and 4% of controls (p less than 0.001). LJM was noted in 131 (55%) of the 238 patients with insulin-dependent diabetes mellitus (IDDM) as opposed to 31 of the 41 patients (76%) with non-insulin-dependent diabetes mellitus (NIDDM). LJM occurred in 60 of the 82 diabetic subjects (73%) receiving insulin therapy who developed diabetes after the age of 35 years. LJM was significantly related to duration of diabetes in the patients with IDDM less than 40 years of age but was not associated with duration in the patients with NIDDM. A significant association of LJM and neuropathy was noted in patients less than 40 years of age with less than 20 years of diabetes. A significant association of LJM and retinopathy was also noted in those less than 40 years of age with less than 30 years of diabetes. There was no association of LJM and nephropathy regardless of age or duration of diabetes.
通过视觉检查对361名年龄在11至83岁的糖尿病门诊患者以及45名无关节炎迹象的非糖尿病对照者的手部关节活动受限（LJM）情况进行了研究。58%的糖尿病患者存在LJM，而对照者中这一比例为4%（p<0.001）。在238例胰岛素依赖型糖尿病（IDDM）患者中有131例（55%）出现LJM，相比之下，41例非胰岛素依赖型糖尿病（NIDDM）患者中有31例（76%）出现LJM。在35岁以后患糖尿病且接受胰岛素治疗的82例糖尿病患者中，有60例（73%）出现LJM。年龄小于40岁的IDDM患者中，LJM与糖尿病病程显著相关，但在NIDDM患者中则与病程无关。在糖尿病病程小于20年且年龄小于40岁的患者中，LJM与神经病变存在显著关联。在糖尿病病程小于30年且年龄小于40岁的患者中，LJM与视网膜病变也存在显著关联。无论年龄或糖尿病病程如何，LJM与肾病均无关联。
Zotero 插件