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中风后性功能障碍——当前综述

Post stroke sexual dysfunction - a current review.

作者信息

Zhang Zhehao, Deng Lan, Lv Xin-Ni, Li Zuo-Qiao, Li Qi

机构信息

Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Department of Neurology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

出版信息

Neurol Sci. 2025 Feb;46(2):605-615. doi: 10.1007/s10072-024-07841-w. Epub 2024 Oct 30.

DOI:10.1007/s10072-024-07841-w
PMID:39472362
Abstract

INTRODUCTION

Sexual dysfunction manifests as various challenges during sexual activity and is a prevalent condition that significantly impacts quality of life. Post stroke sexual dysfunction (PSSD) is particularly concerning, yet it is often overlooked by both healthcare providers and patients.

METHODS

We conducted a comprehensive literature review, examining research and reports related to sexual dysfunction following stroke. Our aim is to synthetize an extensive, detailed and up-to-date overview of its prevalence, underlying mechanisms, and interventions.

RESULTS AND CONCLUSION

PSSD, often underestimated among stroke survivors, has a high incidence but remains poorly understood in terms of its neurobiological mechanisms. Swift and accurate diagnosis, coupled with timely rehabilitative intervention, is crucial. However, the development of comprehensive guidelines is impeded by a lack of high-quality literature. This review seeks to present recent advances in understanding PSSD, and to advocate for a structured strategy in terms of the long-term rehabilitation of stroke survivors.

摘要

引言

性功能障碍表现为性活动中的各种挑战,是一种普遍存在的状况,严重影响生活质量。中风后性功能障碍(PSSD)尤其令人担忧,但往往被医疗服务提供者和患者忽视。

方法

我们进行了全面的文献综述,研究与中风后性功能障碍相关的研究和报告。我们的目的是综合其患病率、潜在机制和干预措施的广泛、详细且最新的概述。

结果与结论

PSSD在中风幸存者中常常被低估,发病率很高,但在神经生物学机制方面仍知之甚少。快速准确的诊断以及及时的康复干预至关重要。然而,由于缺乏高质量的文献,全面指南的制定受到阻碍。本综述旨在介绍在理解PSSD方面的最新进展,并倡导针对中风幸存者长期康复的结构化策略。

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本文引用的文献

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Lesion Network Mapping for Neurological Deficit in Acute Ischemic Stroke.急性缺血性脑卒中神经功能缺损的病灶网络图谱。
Ann Neurol. 2023 Sep;94(3):572-584. doi: 10.1002/ana.26721. Epub 2023 Jun 27.
2
The Risk of Cardiovascular and Cerebrovascular Disease in Men With a History of Priapism.患有阴茎异常勃起病史的男性发生心血管和脑血管疾病的风险
J Urol. 2023 Jan;209(1):253-260. doi: 10.1097/JU.0000000000002962. Epub 2022 Sep 9.
3
Life satisfaction and its influencing factors of middle-aged and elderly stroke patients in China: a national cross-sectional survey.
中国中老年脑卒中患者的生活满意度及其影响因素:一项全国性横断面调查。
BMJ Open. 2022 Aug 3;12(8):e059663. doi: 10.1136/bmjopen-2021-059663.
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Post-stroke outcomes predicted from multivariate lesion-behaviour and lesion network mapping.基于多变量病变行为和病变网络映射预测卒中后结局。
Brain. 2022 May 24;145(4):1338-1353. doi: 10.1093/brain/awac010.
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Poststroke Erectile Dysfunction in Cameroon: Prevalence, Associated Factors, and Quality of Life.喀麦隆中风后勃起功能障碍:患病率、相关因素及生活质量
Stroke Res Treat. 2021 Dec 3;2021:9988841. doi: 10.1155/2021/9988841. eCollection 2021.
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Assessing sexual dysfunction among stroke survivors and barriers to address this issue by physicians at a Latin American reference hospital.在一家拉丁美洲的参考医院评估中风幸存者的性功能障碍以及医生解决这一问题的障碍。
Clin Neurol Neurosurg. 2021 Apr 20;205:106642. doi: 10.1016/j.clineuro.2021.106642.
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Post-stroke depression: A 2020 updated review.中风后抑郁:2020年更新综述。
Gen Hosp Psychiatry. 2020 Sep-Oct;66:70-80. doi: 10.1016/j.genhosppsych.2020.06.011. Epub 2020 Jun 27.
8
Interventions for sexual dysfunction following stroke.中风后性功能障碍的干预措施。
Cochrane Database Syst Rev. 2020 May 1;5(5):CD011189. doi: 10.1002/14651858.CD011189.pub2.
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Antidepressant-induced sexual dysfunction.抗抑郁药引起的性功能障碍。
Med J Aust. 2020 Apr;212(7):329-334. doi: 10.5694/mja2.50522. Epub 2020 Mar 15.
10
Sexual dysfunction after stroke-A biopsychosocial perspective.中风后性功能障碍的生物心理社会视角。
Int J Clin Pract. 2020 Jul;74(7):e13496. doi: 10.1111/ijcp.13496. Epub 2020 Mar 5.