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鸽子源1型禽副粘病毒分离株的抗原性和生物学特性

Antigenic and biological characterization of avian paramyxovirus type 1 isolates from pigeons.

作者信息

Meulemans G, Gonze M, Carlier M C, Petit P, Burny A, Long L

出版信息

Arch Virol. 1986;87(3-4):151-61. doi: 10.1007/BF01315295.

Abstract

21 A/PMV-1 viruses were isolated from pigeons and characterized using polyclonal and monoclonal antisera in hemagglutination inhibition, seroneutralization and immunoprecipitation studies. Polyclonal and monoclonal antibodies directed against the HN and F proteins of Italien virus reacted with all pigeon isolates showing a close relationship between chicken velogenic and pigeon viruses. Differences in the M.W. of F0, P and M proteins were however observed between pigeon and chicken Italien virus. Marked differences in virulence were recorded among pigeon isolates; these were reflected by great variation in the IVPI of the different strains.

摘要

从鸽子中分离出21株A/PMV - 1病毒,并在血凝抑制、血清中和及免疫沉淀研究中使用多克隆和单克隆抗血清对其进行鉴定。针对意大利病毒的HN和F蛋白的多克隆和单克隆抗体与所有鸽子分离株发生反应,表明鸡速发型病毒和鸽子病毒之间存在密切关系。然而,在鸽子和鸡的意大利病毒之间观察到F0、P和M蛋白的分子量存在差异。在鸽子分离株中记录到毒力存在显著差异;这些差异通过不同毒株的静脉内接种致病指数(IVPI)的巨大变化得以体现。

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