Bergeisen G H, Bauman R J, Gilmore R L
Arch Neurol. 1986 Feb;43(2):192-4. doi: 10.1001/archneur.1986.00520020078027.
Neonatal poliomyelitis, which was rare even when poliomyelitis was widespread, has not been reported in the United States since use of live oral poliovirus vaccine (Sabin's vaccine) became widespread. We report a child who became symptomatic with apnea at 18 days of age and who subsequently developed a permanent monoparesis. Serologic and cultural evidence indicated the virus as poliovirus vaccine type. Another infant who received live oral poliovirus vaccine was probably the source of the infecting virus. Recognition that poliovirus infection can still occur in the United States and an understanding of the serologic, cultural, and typing tests required to substantiate this diagnosis are needed so that such patients will be accurately diagnosed.
新生儿脊髓灰质炎,即使在脊髓灰质炎广泛流行时也很罕见,自从口服脊髓灰质炎活疫苗(萨宾疫苗)广泛使用以来,美国就没有报告过此类病例。我们报告了一名18天大时出现呼吸暂停症状并随后发展为永久性单瘫的儿童。血清学和培养证据表明该病毒为脊髓灰质炎疫苗株型。另一名接种口服脊髓灰质炎活疫苗的婴儿可能是感染病毒的来源。需要认识到脊髓灰质炎病毒感染在美国仍可能发生,并了解证实这一诊断所需的血清学、培养和分型检测,以便能准确诊断此类患者。