Innovative Dental Materials and Interfaces Research Unit, Paris Cité University, 1 rue Maurice Arnoux, Montrouge, 92120, France.
Department of Odontology, Bretonneau Hospital AP-HP, Paris, France.
BMC Oral Health. 2024 Oct 29;24(1):1317. doi: 10.1186/s12903-024-05078-9.
The study aimed to examine the prevalence of gingival cancers compared to other oral mucosal sites, analyze patient profiles, and identify risk factors.
A retrospective monocentric study was conducted at the Department of Oral Medicine of Bretonneau Hospital in Paris, France. 32 patients diagnosed with oral mucosal cancer were included. Data extracted from electronic medical records encompassed patient demographics, cancer type, lesion location, and tobacco/alcohol use.
46.9% were diagnosed with gingival cancer. Patients with gingival cancer had a mean age of 74.2 years old, higher than the mean age of 63.9 years old for those with non-gingival cancer. Men accounted for 60% of cases in the gingival cancer group. Squamous cell carcinoma was the predominant cancer type observed in both gingival and non-gingival cancers. Notably, 26.7% of gingival cancer patients used both alcohol and tobacco, all of them male. Among non-gingival cancer patients, 23.5% used both substances, with both sexes represented.
This study provides insights into the higher prevalence of oral squamous cell carcinoma among men with risk factors and highlights characteristics of gingival squamous cell carcinoma. Effective management strategies should include comprehensive clinical assessments to ensure early detection and intervention for improved outcomes.
本研究旨在比较牙龈癌与其他口腔黏膜部位的发病率，分析患者特征，并确定风险因素。
这是一项在法国巴黎 Bretonneau 医院口腔医学系进行的回顾性单中心研究。共纳入 32 名口腔黏膜癌患者。从电子病历中提取的数据包括患者人口统计学、癌症类型、病变位置以及烟草/酒精使用情况。
46.9%的患者被诊断为牙龈癌。与非牙龈癌患者的平均年龄 63.9 岁相比，患有牙龈癌的患者平均年龄为 74.2 岁。在牙龈癌组中，男性占 60%。在牙龈癌和非牙龈癌中，均观察到以鳞状细胞癌为主的癌症类型。值得注意的是，26.7%的牙龈癌患者同时使用酒精和烟草，均为男性。在非牙龈癌患者中，23.5%的患者同时使用这两种物质，男女均有涉及。
本研究深入了解了男性中具有风险因素的口腔鳞状细胞癌发病率较高的情况，并强调了牙龈鳞状细胞癌的特征。有效的管理策略应包括全面的临床评估，以确保早期发现和干预，从而改善预后。
