Bloom L D, Rowley D
Aust J Exp Biol Med Sci. 1979 Jun;57(3):313-23. doi: 10.1038/icb.1979.34.
Cholera immunization schedules were investigated in mice, with emphasis placed on obtaining an immune response in the intestine. The most effective schedule for producing a good local response was found to be several orally-given priming doses of the organism followed after 14 days by an intravenous boosting dose. Major differences between the immune responses in the spleen and the intestine were noted.
