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Persistence in the mouse gut as an important factor in oral immunogenicity of strains of V. cholerae.

作者信息

Bloom L, Rowley D

出版信息

Aust J Exp Biol Med Sci. 1979 Jun;57(3):325-33. doi: 10.1038/icb.1979.35.

DOI:10.1038/icb.1979.35
PMID:533484
Abstract

The immune responses of mice following oral vaccination with two strains of live V. cholerae have been examined. A strain which persisted in the small intestine was a superior local immunogen by comparison with another non-persisting strain. Local persistence and the ability to induce a local immune response appeared to be correlated, since the two vibrio strains elicited identical responses when given parenterally.

摘要

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