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膝关节镜检查后关节内注射麻醉剂利多卡因和甲基强的松龙与单独注射甲基强的松龙的镇痛效果比较。

Analgesic effects of intraarticular anaesthetic lidocaine and methylprednisolone versus methylprednisolone alone following knee arthroscopy.

作者信息

Hassan Wahid Mohammed, Mohammad Anas Amer

机构信息

University of Duhok, Duhok, Iraq.

出版信息

ADMET DMPK. 2024 Aug 3;12(4):679-685. doi: 10.5599/admet.2412. eCollection 2024.

DOI:10.5599/admet.2412
PMID:39473625
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11517516/
Abstract

BACKGROUND

Knee arthroscopy is a widely practiced orthopaedic procedure known for its minimally invasive approach, allowing quicker recovery times and less postoperative discomfort than traditional open surgeries. However, managing postoperative pain remains a critical aspect of patient care and satisfaction. The main objective of this research is to examine the relationships between patient demographics (age, gender, BMI) and early postoperative outcomes, including pain, physiotherapy, and walking.

METHOD

Randomized data collection, clinical trial study of 2 groups of patients. The patients were split into lidocaine 1 % 16 ml + methylprednisolone 160 mg 4 ml) and (methylprednisolone only 160 mg 4 ml) groups. All patients in both groups were queried about age, gender, BMI, and pain on the first, third, and 15th days following surgery. All patients were tested for physiotherapy on the second, third, and fourth postop days. After surgery, walking was tested on the third, fourth, and fifth days.

RESULTS

Significant differences in postoperative pain relief and physiotherapy initiation times were observed. There are notable associations between treatment groups and recovery metrics, such as pain levels and mobility on various days' post-surgery. Significant demographic influences (age, gender, BMI) on recovery outcomes are observed, particularly in walking and pain at day 15 post-operation.

CONCLUSION

lidocaine and methylprednisolone improve postoperative pain relief and functional recovery in knee arthroscopy patients, with most experiencing reduced pain early post-surgery (early physiotherapy) and an expedited return to walking (decreased morbidity). Patients taking just methylprednisolone recovered slower. Age, gender, and BMI affected pain and walking abilities post-operation but not physiotherapy time, underscoring the personalised approach needed in postoperative treatment.

摘要

背景

膝关节镜检查是一种广泛应用的骨科手术,以其微创方法著称,与传统开放性手术相比,恢复时间更快,术后不适更少。然而,管理术后疼痛仍然是患者护理和满意度的关键方面。本研究的主要目的是探讨患者人口统计学特征(年龄、性别、体重指数)与术后早期结果之间的关系,包括疼痛、物理治疗和行走情况。

方法

对两组患者进行随机数据收集和临床试验研究。患者被分为利多卡因1% 16毫升+甲泼尼龙160毫克4毫升组和(仅甲泼尼龙160毫克4毫升)组。两组所有患者均被询问手术后头一天、第三天和第十五天的年龄、性别、体重指数和疼痛情况。所有患者在术后第二天、第三天和第四天接受物理治疗测试。术后第三天、第四天和第五天测试行走情况。

结果

观察到术后疼痛缓解和物理治疗开始时间存在显著差异。治疗组与恢复指标之间存在显著关联,如术后不同天数的疼痛程度和活动能力。观察到人口统计学特征(年龄、性别、体重指数)对恢复结果有显著影响,尤其是在术后第15天的行走和疼痛方面。

结论

利多卡因和甲泼尼龙可改善膝关节镜检查患者的术后疼痛缓解和功能恢复,大多数患者术后早期疼痛减轻(早期物理治疗)且行走恢复加快(发病率降低)。仅服用甲泼尼龙的患者恢复较慢。年龄、性别和体重指数影响术后疼痛和行走能力,但不影响物理治疗时间,这突出了术后治疗需要个性化方法。

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