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手术挽救策略:应对胸壁肉瘤急症

Strategies in Surgical Salvage: Navigating a Chest Wall Sarcoma Emergency.

作者信息

Aleksiev Vladimir, Markov Daniel, Yavorov Boyko, Kitov Spas, Bechev Kristian

机构信息

Cardiovascular Surgery, Medical University of Plovdiv, Plovdiv, BGR.

General and Clinical Pathology, Medical University of Plovdiv, Plovdiv, BGR.

出版信息

Cureus. 2024 Sep 29;16(9):e70424. doi: 10.7759/cureus.70424. eCollection 2024 Sep.

DOI:10.7759/cureus.70424
PMID:39473659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11520029/
Abstract

Soft tissue sarcomas arising from the chest wall are an extremely rare entity. They are classified as mesenchymal tumors of varying aggression. It is this unpredictable behavior that makes them an unexpected hurdle even for experienced surgeons. Given the intricate anatomy of the thorax, any of its various tissues can potentially give rise to a sarcoma. Soft tissue sarcomas, in particular, present a diagnostic and surgical difficulty due to the necessity of complex surgical techniques and the rising need for chest wall reconstruction. These tumors are the subject of multidisciplinary discussions to come to the best therapeutic course. This is precisely what will prevent recurrence and ensure a better understanding of this pathology. In this report, we present the case of a recurrent soft tissue sarcoma that required emergency surgery due to spontaneous bleeding. It perfectly showcases the complicated treatment of such pathologies and is of profound surgical interest as it utilizes a large chest wall resection, coupled with an intricate subcutaneous flap reconstruction. In this report, we tried to outline the critical aspects of sarcoma surgery and presented our method of choice when reconstructing the soft tissues of the chest.

摘要

起源于胸壁的软组织肉瘤是一种极为罕见的疾病。它们被归类为具有不同侵袭性的间充质肿瘤。正是这种不可预测的行为,使得即使对于经验丰富的外科医生来说,它们也是一个意想不到的障碍。鉴于胸部复杂的解剖结构,其任何一种组织都有可能引发肉瘤。特别是软组织肉瘤,由于需要复杂的手术技术以及对胸壁重建的需求不断增加,呈现出诊断和手术上的困难。这些肿瘤是多学科讨论的主题,以确定最佳治疗方案。这恰恰能防止复发,并确保对这种病理状况有更好的理解。在本报告中,我们介绍了一例因自发性出血而需要紧急手术的复发性软组织肉瘤病例。它完美地展示了此类病症的复杂治疗过程,并且由于采用了大面积胸壁切除以及复杂的皮下皮瓣重建,具有深远的外科研究价值。在本报告中,我们试图概述肉瘤手术的关键要点,并介绍我们在重建胸部软组织时所选择的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/be9a8f65757e/cureus-0016-00000070424-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/0a26cfc845d3/cureus-0016-00000070424-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/8f94b4727c9f/cureus-0016-00000070424-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/c236361df1ca/cureus-0016-00000070424-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/43b7c3f05197/cureus-0016-00000070424-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/3eba989364e1/cureus-0016-00000070424-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/0235127e7dc9/cureus-0016-00000070424-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/57398562b34a/cureus-0016-00000070424-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/e0c5405a226f/cureus-0016-00000070424-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/be9a8f65757e/cureus-0016-00000070424-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/0a26cfc845d3/cureus-0016-00000070424-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/8f94b4727c9f/cureus-0016-00000070424-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/c236361df1ca/cureus-0016-00000070424-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/43b7c3f05197/cureus-0016-00000070424-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/3eba989364e1/cureus-0016-00000070424-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/0235127e7dc9/cureus-0016-00000070424-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/57398562b34a/cureus-0016-00000070424-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/e0c5405a226f/cureus-0016-00000070424-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/286c/11520029/be9a8f65757e/cureus-0016-00000070424-i09.jpg

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本文引用的文献

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The Therapeutic Role of Plastic and Reconstructive Surgery in the Interdisciplinary Treatment of Soft-Tissue Sarcomas in Germany-Cross-Sectional Results of a Prospective Nationwide Observational Study (PROSa).德国软组织肉瘤多学科治疗中整形与重建手术的治疗作用——一项全国性前瞻性观察研究(PROSa)的横断面结果
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Myxoid pleomorphic liposarcoma is distinguished from other liposarcomas by widespread loss of heterozygosity and significantly worse overall survival: a genomic and clinicopathologic study.黏液样多形性脂肪肉瘤通过广泛的杂合性丢失和明显更差的总体生存率与其他脂肪肉瘤区分开来:一项基因组和临床病理研究。
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