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智能压力控制输尿管镜联合铥激光治疗孤立性上尿路尿路上皮癌的临床疗效分析

Clinical efficacy analysis of intelligent pressure-controlled ureteroscopy combined with thulium laser in the treatment of isolated upper urinary tract urothelial carcinoma.

作者信息

Chen Hua, Xiao Jiansheng, Ge Jiaqi, Liu Tairong

机构信息

Department of Urology, Ganzhou People's Hospital, Jiangxi Medical College, Nanchang University, Ganzhou, Jiangxi, China.

出版信息

Front Oncol. 2024 Oct 15;14:1406031. doi: 10.3389/fonc.2024.1406031. eCollection 2024.

Abstract

OBJECTIVE

This study aims to investigate the clinical treatment effect of intelligent pressure-controlled ureteroscopy combined with thulium laser for patients with isolated kidney upper tract urothelial carcinoma (UTUC).

METHODS

This study employed a retrospective analysis approach and focused on six patients with isolated kidney UTUC admitted to our hospital from June 2018 to May 2023, who underwent tumor resection surgery using intelligent pressure-controlled ureteroscopy combined with thulium laser. We collected the perioperative clinical data of these six patients and conducted statistical analysis of the treatment effects.

RESULTS

The surgeries of all six patients were completed smoothly, without incidents of surgery termination due to significant bleeding. Postoperative pathology revealed that four patients had low-grade non-invasive papillary urothelial carcinoma, while the other two patients had high-grade invasive urothelial carcinoma. During follow-up period, one patient had a renal pelvis recurrence three months after the surgery, and subsequently underwent thulium laser resection. Additionally, another patient experienced bladder recurrence eight months after the surgery and received transurethral resection of bladder tumor (TURBT) for treatment. The remaining four patients did not experience tumor recurrence during the follow-up.

CONCLUSION

For patients with isolated kidney associated with UTUC, intelligent pressure-controlled ureteroscopy combined with thulium laser represents a feasible treatment option, with good therapeutic effects for low-risk upper tract urothelial carcinoma.

摘要

目的

本研究旨在探讨智能压力控制输尿管镜联合铥激光治疗孤立肾输尿管上段尿路上皮癌(UTUC)患者的临床治疗效果。

方法

本研究采用回顾性分析方法,聚焦于2018年6月至2023年5月期间我院收治的6例孤立肾UTUC患者,这些患者均采用智能压力控制输尿管镜联合铥激光进行肿瘤切除手术。我们收集了这6例患者的围手术期临床资料,并对治疗效果进行了统计分析。

结果

6例患者手术均顺利完成,无因大出血导致手术终止的情况。术后病理显示,4例患者为低级别非浸润性乳头状尿路上皮癌,另外2例患者为高级别浸润性尿路上皮癌。随访期间,1例患者术后3个月肾盂复发,随后接受铥激光切除。此外,另1例患者术后8个月膀胱复发,接受经尿道膀胱肿瘤电切术(TURBT)治疗。其余4例患者随访期间未出现肿瘤复发。

结论

对于合并UTUC的孤立肾患者,智能压力控制输尿管镜联合铥激光是一种可行的治疗选择,对低风险输尿管上段尿路上皮癌具有良好的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5a3/11518684/8abfbf8e9fba/fonc-14-1406031-g001.jpg

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