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提高预测直肠神经内分泌肿瘤的预后准确性。

Enhancing prognostic accuracy in predicting rectal neuroendocrine neoplasms.

机构信息

Department of Medicine, Aston Medical School, Birmingham B4 7ET, United Kingdom.

Department of Nursing & Midwifery Research, Hamad Medical Corporation, Doha 3050, Qatar.

出版信息

World J Gastroenterol. 2024 Oct 7;30(37):4087-4089. doi: 10.3748/wjg.v30.i37.4087.

DOI:10.3748/wjg.v30.i37.4087
PMID:39474400
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11514536/
Abstract

The recently published retrospective study introduces the GATIS score, a new predictive model for rectal neuroendocrine neoplasms. By analyzing data from a large Chinese multicenter cohort, the study shows that the GATIS score, incorporating tumor grade, T stage, tumor size, age, and prognostic nutritional index, demonstrates superior predictive power for overall survival and progression-free survival compared to traditional World Health Organization grade and tumor, nodes and metastases staging systems. This editorial aims to discuss the importance of the GATIS score, its potential impact on clinical practice, and the strengths and limitations of the study. Finally, it explores the significance, methodology, and clinical implications of these findings.

摘要

最近发表的回顾性研究介绍了 GATIS 评分,这是一种用于预测直肠神经内分泌肿瘤的新模型。通过对来自中国大型多中心队列的数据进行分析,该研究表明,与传统的世界卫生组织分级和肿瘤、淋巴结和转移分期系统相比,包含肿瘤分级、T 分期、肿瘤大小、年龄和预后营养指数的 GATIS 评分在预测总生存期和无进展生存期方面具有更好的预测能力。本社论旨在讨论 GATIS 评分的重要性、其对临床实践的潜在影响、以及研究的优势和局限性。最后,探讨了这些发现的意义、方法学和临床意义。

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World J Gastroenterol. 2025 May 21;31(19):106814. doi: 10.3748/wjg.v31.i19.106814.

本文引用的文献

1
GATIS score for predicting the prognosis of rectal neuroendocrine neoplasms: A Chinese multicenter study of 12-year experience.GATIS 评分预测直肠神经内分泌肿瘤预后的价值:一项中国多中心 12 年经验研究。
World J Gastroenterol. 2024 Jul 28;30(28):3403-3417. doi: 10.3748/wjg.v30.i28.3403.
2
Overview of the 2022 WHO Classification of Neuroendocrine Neoplasms.《2022 年世卫组织神经内分泌肿瘤分类概述》。
Endocr Pathol. 2022 Mar;33(1):115-154. doi: 10.1007/s12022-022-09708-2. Epub 2022 Mar 16.
3
Diagnosis and Management of Rectal Neuroendocrine Tumors (NETs).直肠神经内分泌肿瘤(NETs)的诊断与管理
Diagnostics (Basel). 2021 Apr 25;11(5):771. doi: 10.3390/diagnostics11050771.
4
Global burden of neuroendocrine tumors and changing incidence in Kentucky.肯塔基州神经内分泌肿瘤的全球负担及发病率变化
Oncotarget. 2018 Apr 10;9(27):19245-19254. doi: 10.18632/oncotarget.24983.
5
A nation-wide retrospective epidemiological study of gastroenteropancreatic neuroendocrine neoplasms in china.中国胃肠胰神经内分泌肿瘤的全国性回顾性流行病学研究
Oncotarget. 2017 May 3;8(42):71699-71708. doi: 10.18632/oncotarget.17599. eCollection 2017 Sep 22.