Valerio Maria Rosaria, Gebbia Vittorio, Piazza Dario, Campisi Giuseppina, D'Agati Eleonora, Bazzano Monica
Medical Oncology Unit, University Hospital, University of Palermo, Palermo, Italy.
Chair of Medical Oncology, Kore University of Enna, Enna, Italy.
Case Rep Oncol. 2024 Oct 18;17(1):1174-1182. doi: 10.1159/000541391. eCollection 2024 Jan-Dec.
Metastatic breast cancer (MBC) presents an enduring and significant challenge for affected women, requiring sustained commitment over the years.
This paper presents a case of a woman affected by bone and visceral MBC with a very long 20-year survival, excellent quality of life, and high resilience. She is now 51 years old and underwent quadrantectomy for breast cancer in 2005, and in 2013, she developed a recurrence with bone and liver metastases. Despite the widespread stage of the disease with visceral compromise, the patient was treated with a multidisciplinary approach that included surgery, chemotherapy, radiotherapy, hormone therapy, bone target agents, metabolic radiotherapy, and ozone therapy for medication-related osteonecrosis of the jaw. Multidisciplinary management results in a complete clinical and metabolic response to treatment in a visceral metastatic setting.
This report supports the possibility of achieving unusual survival outcomes in patients with MBC. This study also highlights the importance of resilience in breast cancer patients who continue to manage their disease and pursue treatment for over 2 decades. Understanding these resilience factors can improve clinical practice and support patients' long-term care.
转移性乳腺癌（MBC）对患病女性而言是一项长期且重大的挑战，多年来都需要持续的投入。
本文介绍了一名患有骨和内脏转移性乳腺癌的女性病例，她存活了20年之久，生活质量良好，且具有很强的恢复力。她现年51岁，2005年因乳腺癌接受了象限切除术，2013年出现复发并伴有骨和肝转移。尽管疾病已处于广泛期且累及内脏，但该患者接受了多学科治疗，包括手术、化疗、放疗、激素治疗、骨靶向药物治疗、代谢放疗以及针对药物相关性颌骨坏死的臭氧治疗。多学科管理使患者在内脏转移的情况下对治疗产生了完全的临床和代谢反应。
本报告支持MBC患者有可能获得不同寻常的生存结果。本研究还强调了恢复力在乳腺癌患者中的重要性，这些患者在20多年的时间里持续应对疾病并接受治疗。了解这些恢复力因素可以改善临床实践并支持患者的长期护理。
