中国广西男男性行为者中长效注射用卡博特韦的支付意愿和需求价格弹性

Willingness to pay and price elasticity of demand for long-acting injectable cabotegravir among men who have sex with men in Guangxi, China.

作者信息

Chen Shiwen, Ruan Yuhua, Liu Lu, Pei Hengyan, Jiang Yu, Huang Tengda, Wei Yuxia, Qin Litai, Dai Xuebin, Liu Yu, Liu Junhui, Xie Yihong

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, China.

State Key Laboratory of Infectious Disease Prevention and Control (SKLID), National Center for AIDS/STD Control and Prevention (NCAIDS), Chinese Center for Disease Control and Prevention (China CDC), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, China.

出版信息

Front Pharmacol. 2024 Oct 15;15:1367830. doi: 10.3389/fphar.2024.1367830. eCollection 2024.

DOI:10.3389/fphar.2024.1367830

PMID:39474609

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11518773/

Abstract

OBJECTIVES

There is still no study focused on willingness to pay for long-acting injectable cabotegravir (CAB-LA) after it was available on the market in the United States in 2021. Here, we explored the willingness to pay for CAB-LA and associated factors and price elasticity of demand (PED) of CAB-LA among men who have sex with men (MSM) in Guangxi, China.

METHODS

A cross-sectional study was conducted. Univariate and multivariate ordinal logistic regression analyses were performed to explore the associated factors of willingness to pay for CAB-LA. PED was used to measure the change in the number of participants willing to pay to a change in price.

RESULTS

A total of 1,006 MSM were recruited, among which 84.1% were aged between 18 and 39 years old. The median (interquartile) of the maximum amount of willing to pay for CAB-LA was 200 (100-500) Chinese yuan (CNY) per month. Most (84.2%) were willing to pay less than 600 CNY per month. The number of participants willing to pay for CAB-LA significantly increased with decrease in the price. When the price (CNY per month) decreased from 600 to 500, 500 to 400, 400 to 300, and 300 to 200, PED was 3.13, 1.64, 1.33, and 1.17, respectively. The maximum amount of willing to pay for CAB-LA was positively associated with younger age (vs. ≥40 years group, 18-24 years group, aOR: 1.94, 95% CI: 1.32-2.85; 25-39 year group, aOR: 1.70, 95% CI: 1.20-2.42), being high educated (vs. middle school or lower group, high school or college group, aOR: 1.61, 95% CI: 1.06-2.48; bachelor's degree or above group, aOR: 2.21, 95% CI: 1.41-3.49), monthly income ≥6000 CNY (vs. <3000 CNY, aOR: 1.46, 95% CI: 1.02-2.09), being bisexual/unsure sexual orientation (vs. gay, aOR: 1.73, 95% CI: 1.24-2.43), and heard of PrEP and used (vs. never heard of PrEP, aOR: 1.76, 95% CI: 1.11-2.77).

CONCLUSION

The maximum amount of willing to pay for CAB-LA was low in Guangxi, China. PED of CAB-LA is relatively elastic. The waived patent protection should be considered for the wide promotion of CAB-LA, and the health education should be strengthened to improve the recognition of CAB-LA.

摘要

目的

2021年长效注射用卡博特韦（CAB-LA）在美国上市后，仍未有针对其支付意愿的研究。在此，我们探讨了中国广西男男性行为者（MSM）中对CAB-LA的支付意愿、相关因素以及CAB-LA的需求价格弹性（PED）。

方法

进行了一项横断面研究。采用单因素和多因素有序逻辑回归分析来探讨CAB-LA支付意愿的相关因素。PED用于衡量愿意支付的参与者数量随价格变化的情况。

结果

共招募了1006名MSM，其中84.1%年龄在18至39岁之间。CAB-LA每月最大支付意愿的中位数（四分位间距）为200（100 - 500）元人民币（CNY）。大多数（84.2%）愿意每月支付低于600元人民币。愿意为CAB-LA支付的参与者数量随价格降低而显著增加。当价格（每月CNY）从600降至500、500降至400、400降至300以及300降至200时，PED分别为3.13、1.64、1.33和1.17。CAB-LA的最大支付意愿与较年轻年龄（与≥40岁组相比，18 - 24岁组，调整后比值比[aOR]：1.94，95%置信区间[CI]：1.32 - 2.85；25 - 39岁组，aOR：1.70，95% CI：1.20 - 2.42）、高学历（与初中及以下组相比，高中或大专组，aOR：1.61，95% CI：1.06 - 2.48；本科及以上组，aOR：2.21，95% CI：1.41 - 3.49）、月收入≥6000元人民币（与<3000元人民币相比，aOR：1.46，95% CI：1.02 - 2.09）、双性恋/性取向不确定（与同性恋相比，aOR：1.73，95% CI：1.24 - 2.43）以及听说过并使用过暴露前预防（PrEP）（与从未听说过PrEP相比，aOR：1.76，95% CI：1.11 - 2.77）呈正相关。