Department of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, QC, Canada.
Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Jeddah, Jeddah, Saudi Arabia.
J Otolaryngol Head Neck Surg. 2024 Jan-Dec;53:19160216241291808. doi: 10.1177/19160216241291808.
Chronic rhinosinusitis (CRS) significantly impacts patients' quality of life and incurs substantial healthcare costs. Understanding pathogen trends before, during, and after the COVID-19 pandemic can inform better management and treatment strategies.
To identify the common pathogens associated with CRS and compare them across pre-pandemic, during-pandemic, and post-pandemic periods.
Retrospective chart review.
McGill University Health Centre, Montreal, Canada.
Around 147 patients were 18 years and older, diagnosed with CRS, underwent endoscopic sinus surgery within the specified timeframe (January 2017 to September 2023), and whose charts contained relevant microbiology information. Patients were categorized into 3 groups based on surgery dates: pre- (January 2018 to November 2019), during- (January 2020 to December 2021), and post-pandemic (February 2022 to September 2023).
Distribution and prevalence of pathogens associated with CRS across the 3 time periods. Microbiology results from nasal cultures were analyzed to identify predominant pathogens.
Among the 147 patients, 46 distinct organisms were identified. was the most prevalent pathogen, increasing during the COVID-19 period (24.7%) compared to pre-pandemic (17.9%) and post-pandemic (21.5%) periods. Significant increases during the COVID-19 period were noted for (6.8%, < .001), (6.8%, = .01), and (6.8%, = .03). Post-pandemic, significant rises were observed in ( < .001) and ( = .03).
Significant shifts in CRS-associated pathogens occurred during the COVID-19 pandemic. Notable changes in the prevalence of , , , and were observed during the pandemic, with increases in and post-pandemic. These findings suggest that the pandemic's impact on healthcare practices and environmental factors influenced the microbial etiologies of CRS. Future research may explore the mechanisms driving these changes and their long-term implications for CRS management.
慢性鼻-鼻窦炎（CRS）显著影响患者的生活质量，并导致大量医疗保健费用。了解 COVID-19 大流行前后的病原体趋势，可以为更好的管理和治疗策略提供信息。
确定与 CRS 相关的常见病原体，并比较大流行前、大流行中和大流行后时期的这些病原体。
回顾性图表审查。
加拿大麦吉尔大学健康中心。
大约 147 名年龄在 18 岁及以上、被诊断为 CRS、在规定时间内（2017 年 1 月至 2023 年 9 月）接受内镜鼻窦手术，且其图表中包含相关微生物学信息的患者。根据手术日期将患者分为 3 组：大流行前（2018 年 1 月至 2019 年 11 月）、大流行期间（2020 年 1 月至 2021 年 12 月）和大流行后（2022 年 2 月至 2023 年 9 月）。
在 3 个时间段与 CRS 相关的病原体的分布和流行率。对鼻培养物的微生物学结果进行分析，以确定主要病原体。
在 147 名患者中，共发现 46 种不同的生物体。在 COVID-19 期间， 是最常见的病原体（24.7%），高于大流行前（17.9%）和大流行后（21.5%）时期。COVID-19 期间， （6.8%， < .001）、 （6.8%， = .01）和 （6.8%， = .03）的检出率显著升高。大流行后， （ < .001）和 （ = .03）的检出率显著升高。
在 COVID-19 大流行期间，与 CRS 相关的病原体发生了显著变化。在大流行期间， 、 、 和 的流行率显著变化，大流行后 和 的流行率升高。这些发现表明，大流行对医疗保健实践和环境因素的影响影响了 CRS 的微生物病因。未来的研究可能会探讨驱动这些变化的机制及其对 CRS 管理的长期影响。
