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新型冠状病毒肺炎大流行的流行病学模式、耐药特征及临床结局:最新进展与影响

The Epidemiological Pattern, Resistance Characteristics and Clinical Outcome of : Recent Updates and Impact of COVID-19 Pandemic.

作者信息

Hafiz Taghreed A, Albloshi Alaa, Alhumaidan Ohoud S, Mubaraki Murad A, Alyami Ahmed S, Alrashoudi Reem, Alrabiah Mona A, Alotaibi Fawzia

机构信息

Clinical Laboratory Sciences Department, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.

Pathology and Clinical Laboratory Medicine, King Fahad Medical City, Riyadh 11525, Saudi Arabia.

出版信息

Healthcare (Basel). 2023 Jan 19;11(3):312. doi: 10.3390/healthcare11030312.

Abstract

OBJECTIVES

is an opportunistic organism that causes serious infections, particularly in immuno-compromised and hospitalized patients, along with the emergence of resistance traits. The COVID-19 pandemic has impacted the epidemiological pattern and resistance traits of infections as well as those of other bacteria. The study aims to assess the epidemiological patterns, resistance characteristics and clinical outcomes of in Saudi Arabia and the impact of the COVID-19 pandemic.

METHODS

King Fahad Medical City in Riyadh provided the data between January 2019 and December 2021 for the retrospective study of 638 isolates of . The clinical outcome of an infection was also determined by collecting and statistically analyzing the clinical records of 153 ICU patients.

RESULTS

The total percentage of resistant isolates decreased from 48.36% in 2019 to 38% in 2020 and 37.6% in 2021. The overall mortality rate among ICU patients was 40.5%, with an adult age group having a substantial relative risk value of 1.37.

CONCLUSION

is a prevalent nosocomial infection in which adult age is a significant risk factor for mortality. Moreover, this study emphasizes the importance of comparing resistance trends before and throughout the pandemic period in order to better understand the bacteria's behaviour.

摘要

目的

是一种机会致病菌,可引发严重感染,尤其是在免疫功能低下和住院患者中,同时还会出现耐药性特征。新冠疫情已经影响了感染以及其他细菌的流行病学模式和耐药性特征。本研究旨在评估沙特阿拉伯的流行病学模式、耐药特征和临床结局以及新冠疫情的影响。

方法

利雅得的法赫德国王医疗城提供了2019年1月至2021年12月期间638株分离株的数据,用于回顾性研究。还通过收集和统计分析153名重症监护病房患者的临床记录来确定感染的临床结局。

结果

耐药分离株的总百分比从2019年的48.36%降至2020年的38%和2021年的37.6%。重症监护病房患者的总体死亡率为40.5%,成人年龄组的相对风险值较高,为1.37。

结论

是一种常见的医院感染,其中成人年龄是死亡率的一个重要风险因素。此外,本研究强调了比较疫情前和疫情期间耐药趋势的重要性,以便更好地了解该细菌的行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a76/9914498/9e1244f9d1d7/healthcare-11-00312-g001.jpg

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